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Clinical and Translational Neuroscience, Volume 6, Issue 1

March 2022 - 8 articles

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Articles (8)

  • Case Report
  • Open Access
2,667 Views
2 Pages

Waning humoral responses to SARS-CoV-2 vaccination have been reported arguing for booster vaccinations even in healthy populations. Multiple sclerosis (MS) immunotherapy with anti-CD20 monoclonal antibodies may negatively influence morbidity and mort...

  • Review
  • Open Access
4 Citations
4,122 Views
7 Pages

Hot Topics on COVID-19 and Its Possible Association with Guillain-Barré Syndrome

  • Anelia Dietmann,
  • Paolo Ripellino,
  • Andrea M. Humm,
  • Thomas Hundsberger,
  • Bettina Schreiner,
  • Marie Théaudin and
  • Olivier Scheidegger

As the COVID-19 pandemic progresses, reports of neurological manifestations are increasing. However, despite a high number of case reports and case series on COVID-19 and Guillain-Barré-Syndrome (GBS), a causal association is still highly deba...

  • Article
  • Open Access
3,342 Views
6 Pages

COVID-19 in a Neuroimmunological Outpatient Cohort: The Bernese Experience

  • Maximilian Pistor,
  • Anke Salmen,
  • Andrew Chan and
  • Robert Hoepner

The COVID-19 pandemic specifically affects the management and treatment of patients with autoimmune neurological disorders. Major concerns include potentially higher risks of infection or severe disease course under certain immunotherapies used to tr...

  • Review
  • Open Access
6 Citations
8,376 Views
19 Pages

Cortical Hyperexcitability in the Driver’s Seat in ALS

  • Zeynep I. Gunes,
  • Vanessa W. Y. Kan,
  • Shenyi Jiang,
  • Evgeny Logunov,
  • XiaoQian Ye and
  • Sabine Liebscher

Amyotrophic lateral sclerosis (ALS) is a fatal disease characterized by the degeneration of cortical and spinal motor neurons. With no effective treatment available to date, patients face progressive paralysis and eventually succumb to the disease du...

  • Article
  • Open Access
3,711 Views
13 Pages

From Diagnosis to Satisfaction in Multiple Sclerosis: A Swiss Patient Survey Highlighting the Importance of the First Diagnostic Consultation

  • Christian P. Kamm,
  • Praveen Manjakunnel,
  • Dirk Lehnick,
  • Martin Welter,
  • Andrew Chan,
  • Nicole Kamber and
  • Tim Vanbellingen

Background: An early treatment start with disease modifying therapies (DMT) and long-term adherence is crucial in the treatment of people with multiple sclerosis (PwMS) to prevent future disability. Objectives: To gain information on the diagnostic p...

  • Review
  • Open Access
12,805 Views
38 Pages

The objective of this article is to provide a comprehensive personal survey of all the major parasomnias with coverage of their clinical presentation, investigation, physiopathogenesis and treatment. These include the four major members of the slow-w...

  • Review
  • Open Access
6 Citations
17,046 Views
19 Pages

Management of Functional Neurological Disorders (FND): Experience from a Swiss FND Clinic

  • Anita Barbey,
  • Irena Pjanic,
  • Helene Studer,
  • Nina Bischoff,
  • Claudio L. A. Bassetti and
  • Selma Aybek

Functional neurological disorder (FND) represent a common disorder with significant socio-economic impact. In this context and alongside recent new neuroscientific insights, FND attracts a growing interest both in clinical practice and academic activ...

  • Review
  • Open Access
4,405 Views
5 Pages

Neurologic Complications in Adult and Pediatric Patients with SARS-CoV-2 Infection

  • Kendall Howard,
  • Taylor Williams,
  • Elizabeth Fitch,
  • Heather Ots,
  • Esther Pototskiy,
  • Jay Hawkshead,
  • Zelda Ghersin and
  • Alberto E. Musto

SARS-CoV-2 has an impact on the nervous system as a result of pathological cellular and molecular events at the level of vascular and neural tissue. Severe neurologic manifestations including stroke, ataxia, seizure, and depressed level of consciousn...

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Clin. Transl. Neurosci. - ISSN 2514-183X