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Ultrasound Assisted Green One Pot Synthesis of Bound Type bis-Heterocyclic furan-2-yl imidazo [1,2-a] Pyridines via GBBR

Departamento de Química, Universidad de Guanajuato, Noria Alta S/N, Col. Noria Alta, C.P. 36050 Guanajuato, Gto., Mexico
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Presented at the 22nd International Electronic Conference on Synthetic Organic Chemistry, 15 November- 15 December 2018; Available Online: https://sciforum.net/conference/ecsoc-22.
Proceedings 2019, 9(1), 46; https://doi.org/10.3390/ecsoc-22-05799
Published: 14 November 2018
PDF [266 KB, uploaded 17 April 2019]

Abstract

A series of six new 3-imidazo[1,2-a] pyridine furan bound type tris-heterocycles were synthesized by Ultrasound Irradiation (USI) assisted Groebke-Blackburn-Bienaymé reaction (GBBR), by employing ammonium chloride (10 mol%) as a catalyst in excellent yields (80–93%) under green conditions. This efficient and mild protocol has silent features such as green inexpensive and easily available catalyst and solvent at room temperature.
Keywords: Ultrasound-GBBR; tris-heterocycles; green catalyst; green one pot process Ultrasound-GBBR; tris-heterocycles; green catalyst; green one pot process
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
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Kurva, M.; Gámez-Montaño, R. Ultrasound Assisted Green One Pot Synthesis of Bound Type bis-Heterocyclic furan-2-yl imidazo [1,2-a] Pyridines via GBBR. Proceedings 2019, 9, 46.

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