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Implication of Magnetic Nanoparticles in Cancer Detection, Screening and Treatment

Department of Analytical Chemistry, Faculty of Pharmacy, Iuliu Haţieganu University of Medicine and Pharmacy, 4 Pasteur Street, 400349 Cluj-Napoca, Romania
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Author to whom correspondence should be addressed.
These authors contributed equally to this work.
Magnetochemistry 2019, 5(4), 55; https://doi.org/10.3390/magnetochemistry5040055
Received: 30 August 2019 / Revised: 25 September 2019 / Accepted: 27 September 2019 / Published: 1 October 2019
(This article belongs to the Special Issue Magnetic Nanoparticles)
During the last few decades, magnetic nanoparticles have been evaluated as promising materials in the field of cancer detection, screening, and treatment. Early diagnosis and screening of cancer may be achieved using magnetic nanoparticles either within the magnetic resonance imaging technique and/or sensing systems. These sensors are designed to selectively detect specific biomarkers, compounds that can be related to the onset or evolution of cancer, during and after the treatment of this widespread disease. Some of the particular properties of magnetic nanoparticles are extensively exploited in cancer therapy as drug delivery agents to selectively target the envisaged location by tailored in vivo manipulation using an external magnetic field. Furthermore, individualized treatment with antineoplastic drugs may be combined with magnetic resonance imaging to achieve an efficient therapy. This review summarizes the studies about the implications of magnetic nanoparticles in cancer diagnosis, treatment and drug delivery as well as prospects for future development and challenges of magnetic nanoparticles in the field of oncology. View Full-Text
Keywords: magnetic nanoparticles (MNPs); cancer biomarkers; MNPs synthesis; MNPs functionalization; sensors; cancer detection; cancer treatment; cancer screening; magnetic/targeted drug delivery magnetic nanoparticles (MNPs); cancer biomarkers; MNPs synthesis; MNPs functionalization; sensors; cancer detection; cancer treatment; cancer screening; magnetic/targeted drug delivery
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Hosu, O.; Tertis, M.; Cristea, C. Implication of Magnetic Nanoparticles in Cancer Detection, Screening and Treatment. Magnetochemistry 2019, 5, 55.

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