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Fermentation 2018, 4(2), 29;

Evaluation of Sweet Sorghum Juice for the Production of Lysine Using Corynebacterium glutamicum

Sustainable Biofuels and Coproducts Research Unit, Eastern Regional Research Center, USDA, ARS. 600 East Mermaid Lane, Wyndmoor, PA 19038, USA
Author to whom correspondence should be addressed.
Received: 14 March 2018 / Revised: 13 April 2018 / Accepted: 14 April 2018 / Published: 19 April 2018
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Sweet sorghum juice is a liquid sugar feedstock that can be produced in non-tropical climates. Utilization of sweet sorghum juice as a feedstock for the production of lysine was investigated utilizing the auxotrophic mutant Corynebacterium glutamicum ATCC 21513 in stirred tank bioreactors. The juice was found to have inadequate nutrients for growth of the auxotroph alone and was supplemented with two levels of yeast extract and peptone. The supplemented juice could support growth and produce lysine from the available sugars. No inhibitory effects of the juice were found on the growth of the organism. The lysine concentrations reach 28.8 g/L in the batch fermentations with complete utilization of the available sugars and a conversion efficiency of 0.23 g/g. View Full-Text
Keywords: lysine; sorghum; amino acids; bioconversion; Corynebacterium lysine; sorghum; amino acids; bioconversion; Corynebacterium

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Johnston, D.B.; Nghiem, N. Evaluation of Sweet Sorghum Juice for the Production of Lysine Using Corynebacterium glutamicum. Fermentation 2018, 4, 29.

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