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Review

Computational Methods for Fluid-Structure Interaction Simulation of Heart Valves in Patient-Specific Left Heart Anatomies

1
Department of Civil, Construction, and Environmental Engineering, Biomedical Engineering Program, North Dakota State University, Fargo, ND 58105, USA
2
Department of Mechanical Engineering, Georgia Institute of Technology, Atlanta, GA 30332, USA
3
Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA 30332, USA
4
Department of Mechanical and Nuclear Engineering, Virginia Commonwealth University, Richmond, VA 23284, USA
*
Author to whom correspondence should be addressed.
Academic Editor: Rajat Mittal
Fluids 2022, 7(3), 94; https://doi.org/10.3390/fluids7030094
Received: 18 January 2022 / Revised: 23 February 2022 / Accepted: 1 March 2022 / Published: 4 March 2022
(This article belongs to the Special Issue Computational Biofluiddynamics: Advances and Applications)
Given the complexity of human left heart anatomy and valvular structures, the fluid–structure interaction (FSI) simulation of native and prosthetic valves poses a significant challenge for numerical methods. In this review, recent numerical advancements for both fluid and structural solvers for heart valves in patient-specific left hearts are systematically considered, emphasizing the numerical treatments of blood flow and valve surfaces, which are the most critical aspects for accurate simulations. Numerical methods for hemodynamics are considered under both the continuum and discrete (particle) approaches. The numerical treatments for the structural dynamics of aortic/mitral valves and FSI coupling methods between the solid Ωs and fluid domain Ωf are also reviewed. Future work toward more advanced patient-specific simulations is also discussed, including the fusion of high-fidelity simulation within vivo measurements and physics-based digital twining based on data analytics and machine learning techniques. View Full-Text
Keywords: heart valves; fluid–structure interaction; data fusion heart valves; fluid–structure interaction; data fusion
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MDPI and ACS Style

Le, T.B.; Usta, M.; Aidun, C.; Yoganathan, A.; Sotiropoulos, F. Computational Methods for Fluid-Structure Interaction Simulation of Heart Valves in Patient-Specific Left Heart Anatomies. Fluids 2022, 7, 94. https://doi.org/10.3390/fluids7030094

AMA Style

Le TB, Usta M, Aidun C, Yoganathan A, Sotiropoulos F. Computational Methods for Fluid-Structure Interaction Simulation of Heart Valves in Patient-Specific Left Heart Anatomies. Fluids. 2022; 7(3):94. https://doi.org/10.3390/fluids7030094

Chicago/Turabian Style

Le, Trung Bao, Mustafa Usta, Cyrus Aidun, Ajit Yoganathan, and Fotis Sotiropoulos. 2022. "Computational Methods for Fluid-Structure Interaction Simulation of Heart Valves in Patient-Specific Left Heart Anatomies" Fluids 7, no. 3: 94. https://doi.org/10.3390/fluids7030094

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