Peer-Review Record
A Collagen-Mimetic Organic-Inorganic Hydrogel for Cartilage Engineering
Gels 2021, 7(2), 73; https://doi.org/10.3390/gels7020073
by
Laurine Valot 1,2,†
, Marie Maumus 3,4,†, Luc Brunel 1, Jean Martinez 1, Muriel Amblard 1, Danièle Noël 3,*, Ahmad Mehdi 2,* and Gilles Subra 1,*
, Marie Maumus 3,4,†, Luc Brunel 1, Jean Martinez 1, Muriel Amblard 1, Danièle Noël 3,*, Ahmad Mehdi 2,* and Gilles Subra 1,*Reviewer 1:
Anonymous
Reviewer 2:
Anonymous
Gels 2021, 7(2), 73; https://doi.org/10.3390/gels7020073
Submission received: 20 May 2021
/
Revised: 4 June 2021
/
Accepted: 12 June 2021
/
Published: 15 June 2021
(This article belongs to the Special Issue Collagen-Based Hydrogels: Volume II)
Round 1
Reviewer 1 Report
see attached.
Comments for author File: 
Comments.pdf
Author Response
See cover letter
Author Response File: Author Response.pdf
Reviewer 2 Report
In this contribution by Valot and Maumus, and co-workers, the authors developed a novel collagen-mimetic organic-inorganic hydrogel for cartilage regeneration. The results are interesting and potentially attractive to the readership of Gels. However, some corrections are needed in order to increase the overall quality of the paper before publication.
- Many errors occur possibly due to refs in the section of ‘Results and discussion’.
- The quality of figure 3,5, and 6 should be improved (including the resolution of the images).
- One scheme to show how the hydrogel formed by self-assembly and biorthogonal sol-gel cross-linking should be added.
- No figure 9 is found in the ms.
- Cell number decreased after 21 days of culture compared to day 1 significantly. The authors should compare the results with recent studies (doi.org/10.1016/j.actbio.2020.04.027; org/10.1021/acs.biomac.0c00623) where not significant decreasing of cells was found.
Author Response
See cover letter please
Author Response File: Author Response.pdf
Round 2
Reviewer 2 Report
I recommend it for publication in the current form.
