Next Article in Journal
Inactivation of Dermatophytes Causing Onychomycosis and Its Therapy Using Non-Thermal Plasma
Next Article in Special Issue
Outcomes of Antifungal Prophylaxis in High-Risk Haematological Patients (AML under Intensive Chemotherapy): The SAPHIR Prospective Multicentre Study
Previous Article in Journal
Systemic Fusariosis: A Rare Complication in Children with Acute Lymphoblastic Leukemia
Previous Article in Special Issue
Clonal Expansion of Environmental Triazole Resistant Aspergillus fumigatus in Iran
Review

Novel Antifungal Agents and Their Activity against Aspergillus Species

Institute of Hygiene and Medical Microbiology, Medical University Innsbruck, 6020 Innsbruck, Austria
*
Author to whom correspondence should be addressed.
J. Fungi 2020, 6(4), 213; https://doi.org/10.3390/jof6040213
Received: 8 September 2020 / Revised: 30 September 2020 / Accepted: 7 October 2020 / Published: 9 October 2020
(This article belongs to the Special Issue Aspergillus Infection)
There is a need for new antifungal agents, mainly due to increased incidence of invasive fungal infections (IFI), high frequency of associated morbidity and mortality and limitations of the current antifungal agents (e.g., toxicity, drug–drug interactions, and resistance). The clinically available antifungals for IFI are restricted to four main classes: polyenes, flucytosine, triazoles, and echinocandins. Several antifungals are hampered by multiple resistance mechanisms being present in fungi. Consequently, novel antifungal agents with new targets and modified chemical structures are required to combat fungal infections. This review will describe novel antifungals, with a focus on the Aspergillus species. View Full-Text
Keywords: novel antifungal drugs; new therapies; invasive fungal infections; aspergillosis novel antifungal drugs; new therapies; invasive fungal infections; aspergillosis
Show Figures

Figure 1

MDPI and ACS Style

Vahedi-Shahandashti, R.; Lass-Flörl, C. Novel Antifungal Agents and Their Activity against Aspergillus Species. J. Fungi 2020, 6, 213. https://doi.org/10.3390/jof6040213

AMA Style

Vahedi-Shahandashti R, Lass-Flörl C. Novel Antifungal Agents and Their Activity against Aspergillus Species. Journal of Fungi. 2020; 6(4):213. https://doi.org/10.3390/jof6040213

Chicago/Turabian Style

Vahedi-Shahandashti, Roya, and Cornelia Lass-Flörl. 2020. "Novel Antifungal Agents and Their Activity against Aspergillus Species" Journal of Fungi 6, no. 4: 213. https://doi.org/10.3390/jof6040213

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop