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Vet. Sci. 2017, 4(1), 8;

Hyponatremia as the Presenting Feature of a Pituitary Abscess in a Calf

Department of Veterinary Clinical Medicine, University of Illinois, Urbana, IL 61802, USA
Seventh Wave Laboratories, Maryland Heights, MO 63043, USA
Department of Pathobiology, University of Illinois, Urbana, IL 61802, USA
Author to whom correspondence should be addressed.
Academic Editor: Ir. J.A. Jan Mol
Received: 24 October 2016 / Revised: 10 January 2017 / Accepted: 26 January 2017 / Published: 6 February 2017
(This article belongs to the Special Issue Comparative studies on Endocrine Diseases in Animals and Humans)
Full-Text   |   PDF [6070 KB, uploaded 6 February 2017]   |  


A 2-month-old Simmental heifer presented for acute onset of neurological behavior. Laboratory tests confirmed the presence of hyponatremia, hypochloremia, and hypokalemia that improved with intravenous fluid therapy. Despite an initial cessation of neurological signs, symptoms re-emerged, and the heifer was euthanized due to poor prognosis. A pituitary abscess (Trueperella pyogenes) was observed on gross necropsy, suggesting that the effects of panhypopituitarism (inappropriate anti-diuretic hormone (ADH), adrenocorticotropic hormone (ACTH), and/or thyroid-stimulating hormone (TSH) secretion) may have resulted in the clinical findings. Pituitary abscess syndrome carries a poor prognosis due to the inability to penetrate the area with systemic antibiotic therapy. These findings highlight the unusual clinical presentations that may occur following pituitary abscess syndrome in cattle that practitioners need to consider when determining prognosis. View Full-Text
Keywords: cattle; endocrinopathy; pituitary; SIADH cattle; endocrinopathy; pituitary; SIADH

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Stewart, J.L.; Bates, M.C.; Edwards, B.W.; Aldridge, B.M. Hyponatremia as the Presenting Feature of a Pituitary Abscess in a Calf. Vet. Sci. 2017, 4, 8.

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