Cognitive Function and Consumption of Fruit and Vegetable Polyphenols in a Young Population: Is There a Relationship?
Faculty of Health Sciences, Universidad Católica de San Antonio, 30107 Murcia, Spain
*
Author to whom correspondence should be addressed.
Foods 2019, 8(10), 507; https://doi.org/10.3390/foods8100507
Received: 27 August 2019 / Revised: 30 September 2019 / Accepted: 2 October 2019 / Published: 17 October 2019
(This article belongs to the Special Issue New Insights in (Poly)Phenolic Compounds: From Dietary Sources to Health Evidences)
Scientific evidence has shown the relationship between consumption of fruits and vegetables and their polyphenols with the prevention or treatment of diseases. The aim of this review was to find out whether the same relationship exists between fruits and vegetables and cognitive function, especially memory, in a young population. The mechanisms by which polyphenols of fruits and vegetables can exert cognitive benefits were also evaluated. These compounds act to improve neuronal plasticity through the protein CREB (Camp Response Element Binding) in the hippocampus, modulating pathways of signaling and transcription factors (ERK/Akt). In the same way, brain-derived neurotrophic factor (BDNF) is implicated in the maintenance, survival, growth, and differentiation of neurons. All these effects are produced by an increase of cerebral blood flow and an increase of the blood’s nitric oxide levels and oxygenation.
View Full-Text
Keywords:
cognitive function; polyphenols; flavonoids; CREB protein; BDNF; memory; fruits and vegetables; cerebral blood flow
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited
MDPI and ACS Style
Carrillo, J.Á.; Zafrilla, MP.; Marhuenda, J. Cognitive Function and Consumption of Fruit and Vegetable Polyphenols in a Young Population: Is There a Relationship? Foods 2019, 8, 507. https://doi.org/10.3390/foods8100507
AMA Style
Carrillo JÁ, Zafrilla MP, Marhuenda J. Cognitive Function and Consumption of Fruit and Vegetable Polyphenols in a Young Population: Is There a Relationship? Foods. 2019; 8(10):507. https://doi.org/10.3390/foods8100507
Chicago/Turabian StyleCarrillo, Juan Á.; Zafrilla, M P.; Marhuenda, Javier. 2019. "Cognitive Function and Consumption of Fruit and Vegetable Polyphenols in a Young Population: Is There a Relationship?" Foods 8, no. 10: 507. https://doi.org/10.3390/foods8100507
Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.
Search more from Scilit
