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Extraction and Isolation of Kaempferol Glycosides from the Leaves and Twigs of Lindera neesiana

1
Graduate School of Pharmaceutical Sciences, Kumamoto University, 5-1 Oe-honmachi, Chuo-ku, Kumamoto 862-0973, Japan
2
School of Pharmacy, Kumamoto University, 5-1 Oe-honmachi, Chuo-ku, Kumamoto 862-0973, Japan
3
Program for Leading Graduate Schools, Health Life Science: Interdisciplinary and Glocal Oriented (HIGO) Program, Kumamoto University, 5-1 Oe-honmachi, Chuo-ku, Kumamoto 862-0973, Japan
*
Author to whom correspondence should be addressed.
Separations 2019, 6(1), 10; https://doi.org/10.3390/separations6010010
Received: 11 January 2019 / Revised: 29 January 2019 / Accepted: 5 February 2019 / Published: 13 February 2019
(This article belongs to the Special Issue Extraction and Isolation of Natural Products)
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Abstract

The hydroalcoholic extract of leaves and twigs of Lindera neesiana (Wall. ex Nees) Kurz (Lauraceae) was subjected to various column chromatographic methods that isolated five kaempferol glycosides: kaempferol 3-O-β-glucopyranosyl(1→2)-[α-rhamnopyranosyl-(1→6)]-β- glucopyranoside-7-O-α-rhamnopyranoside (1); kaempferol 3-O-β-glucopyranosyl-(1→2)-[α-rhamnopyranosyl (1→6)]-β-glucopyranoside (2); kaempferol 3-O-β-glucopyranosyl(1→2)- α-rhamnopyranoside-7-O-α-rhamnopyranoside (3); kaempferol 3-O-sophoroside (4); and kaempferol 3-O-α-rhamnopyranoside (5). The extract showed moderate free radical scavenging activity and potent pancreatic lipase inhibitory activity. View Full-Text
Keywords: Lindera neesiana; Siltimur; kaempferol glycosides; free radical scavenging; lipase inhibitory Lindera neesiana; Siltimur; kaempferol glycosides; free radical scavenging; lipase inhibitory
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Adhikari-Devkota, A.; Dirar, A.I.; Kurizaki, A.; Tsushiro, K.; Devkota, H.P. Extraction and Isolation of Kaempferol Glycosides from the Leaves and Twigs of Lindera neesiana. Separations 2019, 6, 10.

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