Influence of a Pulsed Electric Field on Charge Generation in a Flowing Protein Solution
AbstractIt is known that a charge is generated in water and protein solutions upon their motion; this phenomenon is also observed in analytical systems for atomic force microscopy (AFM)-based fishing. At that, the efficiency of protein fishing correlates with the value of charge, generated upon the motion of the analyzed solution. Earlier, we demonstrated that a pulsed electric field can well be used for the enhancement of the efficiency of AFM-based fishing of low-abundant protein. In this paper, we have demonstrated the influence of a pulsed electric field on the stimulation of the electric charge generation in a solution of low-abundant proteins observed in the injector part of an AFM-based fishing system at 23 °C and 38 °C. Taking this effect into account is important for the development of novel highly sensitive flow-based diagnostic systems, as well as for the development of models describing the influence of a pulsed electric field on pathological processes in the body, hemodynamics, and physicochemical properties of solutions. View Full-Text
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Ivanov, Y.D.; Kozlov, A.F.; Galiullin, R.A.; Tatur, V.Y.; Ziborov, V.S.; Usanov, S.A.; Pleshakova, T.O. Influence of a Pulsed Electric Field on Charge Generation in a Flowing Protein Solution. Separations 2018, 5, 29.
Ivanov YD, Kozlov AF, Galiullin RA, Tatur VY, Ziborov VS, Usanov SA, Pleshakova TO. Influence of a Pulsed Electric Field on Charge Generation in a Flowing Protein Solution. Separations. 2018; 5(2):29.Chicago/Turabian Style
Ivanov, Yuri D.; Kozlov, Andrey F.; Galiullin, Rafael A.; Tatur, Vadim Y.; Ziborov, Vadim S.; Usanov, Sergey A.; Pleshakova, Tatyana O. 2018. "Influence of a Pulsed Electric Field on Charge Generation in a Flowing Protein Solution." Separations 5, no. 2: 29.
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