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Review

Obstructive Sleep Apnea in Neonates

by
Indira Chandrasekar
1,*,
Mary Anne Tablizo
2,3,
Manisha Witmans
4,
Jose Maria Cruz
5,
Marcus Cummins
6 and
Wendy Estrellado-Cruz
5,*
1
Division of Neonatology, Department of Pediatrics, Valley Children’s Hospital, Madera, CA 94305, USA
2
Division of Pulmonary and Sleep Medicine, Valley Children’s Hospital, Madera, CA 94305, USA
3
Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305, USA
4
Stollery Children’s Hospital, Edmonton, AB T6G 2B7, Canada
5
Department of Pediatrics, Children’s Mercy Hospital, Kansas City, MO 64108, USA
6
School of Medicine, University of California San Francisco, Fresno, CA 94143, USA
*
Authors to whom correspondence should be addressed.
Children 2022, 9(3), 419; https://doi.org/10.3390/children9030419
Submission received: 21 January 2022 / Revised: 4 March 2022 / Accepted: 5 March 2022 / Published: 15 March 2022
(This article belongs to the Section Pediatric Pulmonary and Sleep Medicine)

Abstract

Neonates have distinctive anatomic and physiologic features that predispose them to obstructive sleep apnea (OSA). The overall prevalence of neonatal OSA is unknown, although an increase in prevalence has been reported in neonates with craniofacial malformations, neurological disorders, and airway malformations. If remained unrecognized and untreated, neonatal OSA can lead to impaired growth and development, cardiovascular morbidity, and can even be life threatening. Polysomnography and direct visualization of the airway are essential diagnostic modalities in neonatal OSA. Treatment of neonatal OSA is based on the severity of OSA and associated co-morbidities. This may include medical and surgical interventions individualized for the affected neonate. Based on this, it is expected that infants with OSA have more significant healthcare utilization.
Keywords: neonates; infants; obstructive sleep apnea; upper airway obstruction neonates; infants; obstructive sleep apnea; upper airway obstruction

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MDPI and ACS Style

Chandrasekar, I.; Tablizo, M.A.; Witmans, M.; Cruz, J.M.; Cummins, M.; Estrellado-Cruz, W. Obstructive Sleep Apnea in Neonates. Children 2022, 9, 419. https://doi.org/10.3390/children9030419

AMA Style

Chandrasekar I, Tablizo MA, Witmans M, Cruz JM, Cummins M, Estrellado-Cruz W. Obstructive Sleep Apnea in Neonates. Children. 2022; 9(3):419. https://doi.org/10.3390/children9030419

Chicago/Turabian Style

Chandrasekar, Indira, Mary Anne Tablizo, Manisha Witmans, Jose Maria Cruz, Marcus Cummins, and Wendy Estrellado-Cruz. 2022. "Obstructive Sleep Apnea in Neonates" Children 9, no. 3: 419. https://doi.org/10.3390/children9030419

APA Style

Chandrasekar, I., Tablizo, M. A., Witmans, M., Cruz, J. M., Cummins, M., & Estrellado-Cruz, W. (2022). Obstructive Sleep Apnea in Neonates. Children, 9(3), 419. https://doi.org/10.3390/children9030419

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