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Children 2019, 6(1), 12; https://doi.org/10.3390/children6010012

Neuroblastoma: Tumor Biology and Its Implications for Staging and Treatment

1
Department of Surgery, Children’s Hospital of Wisconsin, Medical College of Wisconsin, Milwaukee, WI 53226, USA
2
Department of Surgery, Children’s Medical Center Dallas, UT Southwestern Medical Center, Dallas, TX 75235, USA
*
Author to whom correspondence should be addressed.
Received: 5 December 2018 / Revised: 8 January 2019 / Accepted: 11 January 2019 / Published: 17 January 2019
(This article belongs to the Special Issue Pediatric Surgical Oncology)
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PDF [2618 KB, uploaded 17 January 2019]
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Abstract

Neuroblastoma, the most common extracranial solid tumor of childhood, has widely variable outcomes dependent on the specific biology of the tumor. In this review, current biologic principles that are used to stratify risk and guide treatment algorithms are discussed. The role for surgical resection in neuroblastoma is also reviewed, including the indications and timing of surgery within the greater treatment plan. View Full-Text
Keywords: neuroblastoma; oncology; pediatric; pathology; surgery neuroblastoma; oncology; pediatric; pathology; surgery
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
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Van Arendonk, K.J.; Chung, D.H. Neuroblastoma: Tumor Biology and Its Implications for Staging and Treatment. Children 2019, 6, 12.

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