Hypoxia and Chromatin: A Focus on Transcriptional Repression Mechanisms
Abstract
:1. Introduction
1.1. Hypoxia
1.2. Chromatin
2. Hypoxia-Induced Chromatin Changes
3. Histone Methylation-Focus on Repression
4. Chromatin Remodelers in Hypoxia-Focus on Repression
5. DNA Methylation in Hypoxia
6. HIF-Dependent Mechanisms of Repression
7. Transcriptional Repression Complexes in Hypoxia
7.1. SIN3A-HDAC
7.2. REST
8. Conclusions
Acknowledgments
Author Contributions
Conflicts of Interest
References
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Writer | Eraser | |
---|---|---|
HMTS | JmjC Histone Demethylases | LSDs |
G9α (H3K9/H3K9me1/me2) | KDM3A (H3K9me1/me2) | LSD1 (H3K9me1/me2) |
GL9 (H3K9/ H3K9me1/me2) | KDM3B (H3K9me1) | (H3K4me1/me2) |
SUV39H1 (H3K9me1/me2) | KDM4A (H3K9me2/me3) | LSD2 |
SUV39H2 (H3K9me1/me2) | KDM4B (H3K9me2/me3) | (H3K4me1/me2) |
SETDB1 (H3K9) | KDM4C (H3K9me2/me3) | |
PRDM2 (H3K9) | KDM4D (H3K9me2/me3) | |
PRDM3 (H3K9) | KDM4E (H3K9me2/me3) | |
PRDM6 (H3K9) | KDM6A (H3K27me2/me3) | |
EZH2 (H3K27/H3K27me1/me2) | KDM6B (H3K27me2/me3) | |
KDM7A (H3K9me1/me2) | ||
(H3K27me1/me2) | ||
PHF2 (H3K9me1/me2) | ||
(H3K27me1/me2) | ||
PHF8 (H3K9me1/me2) | ||
MINA (H3K9me3) |
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Batie, M.; Del Peso, L.; Rocha, S. Hypoxia and Chromatin: A Focus on Transcriptional Repression Mechanisms. Biomedicines 2018, 6, 47. https://doi.org/10.3390/biomedicines6020047
Batie M, Del Peso L, Rocha S. Hypoxia and Chromatin: A Focus on Transcriptional Repression Mechanisms. Biomedicines. 2018; 6(2):47. https://doi.org/10.3390/biomedicines6020047
Chicago/Turabian StyleBatie, Michael, Luis Del Peso, and Sonia Rocha. 2018. "Hypoxia and Chromatin: A Focus on Transcriptional Repression Mechanisms" Biomedicines 6, no. 2: 47. https://doi.org/10.3390/biomedicines6020047
APA StyleBatie, M., Del Peso, L., & Rocha, S. (2018). Hypoxia and Chromatin: A Focus on Transcriptional Repression Mechanisms. Biomedicines, 6(2), 47. https://doi.org/10.3390/biomedicines6020047