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Case Report

Neovascular Glaucoma as the First Symptom of Bilateral Occlusive Retinal Vasculitis in a 4-Year-Old Girl: A Case Report

by
Klaudia Rakusiewicz-Krasnodębska
*,
Joanna Jędrzejczak-Młodziejewska
,
Krystyna Kanigowska
and
Wojciech Hautz
Department of the Pediatric Ophthalmology, Children’s Memorial Health Institute, 04-730 Warsaw, Poland
*
Author to whom correspondence should be addressed.
Biomedicines 2025, 13(1), 148; https://doi.org/10.3390/biomedicines13010148
Submission received: 1 December 2024 / Revised: 4 January 2025 / Accepted: 7 January 2025 / Published: 9 January 2025
(This article belongs to the Special Issue Microcirculation in Health and Diseases)

Abstract

Neovascular glaucoma is a rare and serious condition typically associated with advanced ocular or systemic vascular diseases such as central retinal vein occlusion or diabetic retinopathy. This report describes a unique case of neovascular glaucoma presenting for the first time as an initial symptom of bilateral occlusive retinal vasculitis (ORV) in a generally healthy 4-year-old girl. The patient presented with symptoms of pain and redness in the left eye, accompanied by high intraocular pressure. These symptoms were particularly distressing and uncharacteristic for such a young child. Clinical examination revealed significant findings, including elevated intraocular pressure, corneal edema, and iris neovascularization in the left eye. Additional imaging studies, including fluorescein angiography, demonstrated extensive retinal ischemia with peripheral capillary nonperfusion, confirming the diagnosis of occlusive vasculitis. The management of this case was challenging due to the progressive and aggressive nature of the disease in a 4-year-old patient. This article aims to present the diagnostic and therapeutic strategies for the management of this condition. This report highlights a rare case of neovascular glaucoma as the first manifestation of bilateral ORV in a young child. The unusual presentation emphasizes the need for a high index of suspicion and comprehensive evaluation in cases of pediatric neovascular glaucoma. Early diagnosis and prompt, multimodal treatment are crucial in preventing irreversible vision loss in such cases.
Keywords: neovascular glaucoma; pediatric ophthalmology; occlusive retinal vasculitis (ORV); retinal ischemia; anti-vascular endothelial growth factor therapy neovascular glaucoma; pediatric ophthalmology; occlusive retinal vasculitis (ORV); retinal ischemia; anti-vascular endothelial growth factor therapy

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MDPI and ACS Style

Rakusiewicz-Krasnodębska, K.; Jędrzejczak-Młodziejewska, J.; Kanigowska, K.; Hautz, W. Neovascular Glaucoma as the First Symptom of Bilateral Occlusive Retinal Vasculitis in a 4-Year-Old Girl: A Case Report. Biomedicines 2025, 13, 148. https://doi.org/10.3390/biomedicines13010148

AMA Style

Rakusiewicz-Krasnodębska K, Jędrzejczak-Młodziejewska J, Kanigowska K, Hautz W. Neovascular Glaucoma as the First Symptom of Bilateral Occlusive Retinal Vasculitis in a 4-Year-Old Girl: A Case Report. Biomedicines. 2025; 13(1):148. https://doi.org/10.3390/biomedicines13010148

Chicago/Turabian Style

Rakusiewicz-Krasnodębska, Klaudia, Joanna Jędrzejczak-Młodziejewska, Krystyna Kanigowska, and Wojciech Hautz. 2025. "Neovascular Glaucoma as the First Symptom of Bilateral Occlusive Retinal Vasculitis in a 4-Year-Old Girl: A Case Report" Biomedicines 13, no. 1: 148. https://doi.org/10.3390/biomedicines13010148

APA Style

Rakusiewicz-Krasnodębska, K., Jędrzejczak-Młodziejewska, J., Kanigowska, K., & Hautz, W. (2025). Neovascular Glaucoma as the First Symptom of Bilateral Occlusive Retinal Vasculitis in a 4-Year-Old Girl: A Case Report. Biomedicines, 13(1), 148. https://doi.org/10.3390/biomedicines13010148

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