Inverse Operator over Index Matrices
Abstract
1. Introduction


2. An “Inverse” Operator over Hierarchical Index Matrices
or
), would lead to the “Inverse” operator proposed in the paper.3. Illustrative Example
- K-labels (): Year (from the period 2016–2024),
- L-labels (): Donor’s blood group from the ABO and Rh(D) systems (i.e., O−, O+, A−, A+, B−, B+, AB−, AB+),
- P-labels (): Regions (28 regional subdivisions (centres/departments) of transfusion haematology in Bulgaria),
- Q-labels () Type of donor/donation (—male/voluntary; —male/replacement; —female/voluntary; —female/replacement).
4. Program Implementation of the Operator
5. Discussion
- Blood Group × Region × Year. This data stratification detects regional imbalances in critical blood groups such as the rare blood groups (such as AB– and the universal donor O–), while identifying persistent shortages vs. one-off shocks. Key derived indicators on this basis include the year-on-year growth or decline per blood group and the regional self-sufficiency ratio, while typical resultant decisions may include redistribution of inventory across regions, increased collection targets in specific regions, and investments in regional processing capacity.
- Blood Group × Year. When aggregated on the national level, this data stratification may reveal the long-term trends in rare vs. common blood groups and give an early warning of demographic shifts. This may result in decisions regarding the national donor recruitment priorities, rare donor registry expansion, and long-term agreements for import/export of specific blood and blood products.
- Donor Type × Region × Year. This data stratification helps in the identification of regions over-reliant on replacement donors (of both sexes), and flags cultural or access barriers for women donors (for both types of donation intention). Careful analysis of the data may lead to the development of region- and gender-specific recruitment campaigns in underperforming regions. This is an important aspect to consider, as a higher proportion of replacement donations often signals stress for the healthcare system, while voluntary blood donors are a safer and more sustainable resource. It is noteworthy that the ultimate goal of the World Health Organization is the transition to 100% of voluntary blood donation on a global scale [35], while Bulgaria (with an approximately 15% share on the national level reported for the year 2023 [36]) is still very far from this target.
- Donation Type × Blood Group × Region. Analysis of the data in this stratum is important, as replacement donation availability may vary by blood group and region, and certain blood groups may be disproportionately replacement-based. It is particularly worth analysing the situation with the universal blood donors (O–) and rare blood groups, as the regional characterization may help in case of reserves depletion in certain regions to develop logistic plans and routing of missing blood and blood products from neighbouring regions with adequate availability.
6. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
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Bureva, V.; Atanassov, K.; Atanassova, V.; Umlenski, I. Inverse Operator over Index Matrices. Mathematics 2026, 14, 615. https://doi.org/10.3390/math14040615
Bureva V, Atanassov K, Atanassova V, Umlenski I. Inverse Operator over Index Matrices. Mathematics. 2026; 14(4):615. https://doi.org/10.3390/math14040615
Chicago/Turabian StyleBureva, Veselina, Krassimir Atanassov, Vassia Atanassova, and Ivo Umlenski. 2026. "Inverse Operator over Index Matrices" Mathematics 14, no. 4: 615. https://doi.org/10.3390/math14040615
APA StyleBureva, V., Atanassov, K., Atanassova, V., & Umlenski, I. (2026). Inverse Operator over Index Matrices. Mathematics, 14(4), 615. https://doi.org/10.3390/math14040615

