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Article

The Use of Primary Care Electronic Health Records for Research: Lipid Medications and Mortality in Elderly Patients

1
Graduate Medicine, Faculty of Science, Medicine and Health, University of Wollongong, Wollongong 2522, Australia
2
Illawarra Health and Medical Research Institute, University of Wollongong, Wollongong 2522, Australia
3
Centre for Health Research Illawarra Shoalhaven Population, University of Wollongong, Wollongong 2522, Australia
4
Public Health, Illawarra Shoalhaven Local Health District, Warrawong, NSW 2502, Australia
5
Sydney School of Public Health, University of Sydney, Sydney 2006, Australia
*
Author to whom correspondence should be addressed.
Pharmacy 2019, 7(3), 134; https://doi.org/10.3390/pharmacy7030134
Received: 11 August 2019 / Revised: 4 September 2019 / Accepted: 10 September 2019 / Published: 18 September 2019
(This article belongs to the Special Issue Deprescribing of Problematic Polypharmacy)
General practice electronic health record (EHR) data have significant potential for clinical research. This study demonstrates the feasibility of utilising longitudinal EHR data analysis to address clinically relevant outcomes and uses the relationship between lipid medication prescription and all-cause mortality in the elderly as an exemplar for the validity of this methodology. EHR data were analysed to describe the association of lipid medication use, non-use or cessation with all-cause mortality in patients aged ≥75 years. Survival analysis with Cox regression was used to calculate hazard ratios, which were adjusted for confounders. There was no significant difference in all-cause mortality among patients according to their use, non-use, or cessation of lipid medications. The outcomes of this study correlate well with the results of other research works. This single-practice study demonstrates the feasibility and potential of analysing EHR data to address important clinical issues such as the relationship between all-cause mortality and lipid medication prescription in the elderly. View Full-Text
Keywords: hypolipidemic agents; family practice; electronic health records; survival analysis; aged; aged 80 and over hypolipidemic agents; family practice; electronic health records; survival analysis; aged; aged 80 and over
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MDPI and ACS Style

Hodgkins, A.J.; Mullan, J.; Mayne, D.J.; Bonney, A. The Use of Primary Care Electronic Health Records for Research: Lipid Medications and Mortality in Elderly Patients. Pharmacy 2019, 7, 134. https://doi.org/10.3390/pharmacy7030134

AMA Style

Hodgkins AJ, Mullan J, Mayne DJ, Bonney A. The Use of Primary Care Electronic Health Records for Research: Lipid Medications and Mortality in Elderly Patients. Pharmacy. 2019; 7(3):134. https://doi.org/10.3390/pharmacy7030134

Chicago/Turabian Style

Hodgkins, Adam J., Judy Mullan, Darren J. Mayne, and Andrew Bonney. 2019. "The Use of Primary Care Electronic Health Records for Research: Lipid Medications and Mortality in Elderly Patients" Pharmacy 7, no. 3: 134. https://doi.org/10.3390/pharmacy7030134

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