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Review

Medication Reviews and Clinical Outcomes in Persons with Dementia: A Scoping Review

1
School of Pharmacy, University of Waterloo, 10 Victoria St S A, Kitchener, ON N2G 1C5, Canada
2
Faculty of Health, Western University, 1151 Richmond St, London, ON N6A 5B9, Canada
3
CFFM MINT Memory Clinic, 25 Joseph St, Kitchener, ON N2G 4X6, Canada
4
Schlegel-UW Research Institute for Aging, 250 Laurelwood Dr, Waterloo, ON N2J 0E2, Canada
5
Department of Family Medicine, McMaster University, 100 Main St W 5th Floor, Hamilton, ON L8P 1H6, Canada
*
Author to whom correspondence should be addressed.
Pharmacy 2023, 11(5), 168; https://doi.org/10.3390/pharmacy11050168
Submission received: 6 August 2023 / Revised: 10 October 2023 / Accepted: 16 October 2023 / Published: 20 October 2023
(This article belongs to the Special Issue Pharmacy Reviews in 2022)

Abstract

Persons diagnosed with dementia are often faced with challenges related to polypharmacy and inappropriate medication use and could benefit from regular medication reviews. However, the benefit of such reviews has not been examined in this population. Therefore, the current scoping review was designed to identify the gaps in the current knowledge regarding the impact of medication reviews on the clinical outcomes in older adults with dementia. Relevant studies were identified by searching three databases (Ovid MEDLINE, Ovid EMBASE, and Scopus) from inception to January 2022 with a combination of keywords and medical subject headings. After the removal of duplicates and ineligible articles, 22 publications of the initial 8346 were included in this review. A total of 57 outcomes were identified, including those pertaining to the evaluation of medication use (n = 17), drug-related interventions (n = 11), drug-related problems (n = 10), dementia-related behavioral symptoms (n = 8), cost-effectiveness (n = 2), drug-related hospital admissions (n = 1), as well as outcomes classified as other (n = 7). Gaps identified through this scoping review included the paucity of studies measuring the impact of medication reviews on the medication management capacity and medication adherence, quality of life, and mortality.
Keywords: older adults; dementia; medication review; drug-related problems older adults; dementia; medication review; drug-related problems

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MDPI and ACS Style

Sharma, R.; Mahajan, N.; Fadaleh, S.A.; Patel, H.; Ivo, J.; Faisal, S.; Chang, F.; Lee, L.; Patel, T. Medication Reviews and Clinical Outcomes in Persons with Dementia: A Scoping Review. Pharmacy 2023, 11, 168. https://doi.org/10.3390/pharmacy11050168

AMA Style

Sharma R, Mahajan N, Fadaleh SA, Patel H, Ivo J, Faisal S, Chang F, Lee L, Patel T. Medication Reviews and Clinical Outcomes in Persons with Dementia: A Scoping Review. Pharmacy. 2023; 11(5):168. https://doi.org/10.3390/pharmacy11050168

Chicago/Turabian Style

Sharma, Rishabh, Neil Mahajan, Sarah Abu Fadaleh, Hawa Patel, Jessica Ivo, Sadaf Faisal, Feng Chang, Linda Lee, and Tejal Patel. 2023. "Medication Reviews and Clinical Outcomes in Persons with Dementia: A Scoping Review" Pharmacy 11, no. 5: 168. https://doi.org/10.3390/pharmacy11050168

APA Style

Sharma, R., Mahajan, N., Fadaleh, S. A., Patel, H., Ivo, J., Faisal, S., Chang, F., Lee, L., & Patel, T. (2023). Medication Reviews and Clinical Outcomes in Persons with Dementia: A Scoping Review. Pharmacy, 11(5), 168. https://doi.org/10.3390/pharmacy11050168

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