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Open AccessReview

Ethnobotany, Phytochemistry and Pharmacological Activity of Kigelia africana (Lam.) Benth. (Bignoniaceae)

1
Department of Plant Sciences, Microbiology and Biotechnology, College of Natural Sciences, Makerere University, Kampala 00256, Uganda
2
Phytomedicine Programme, Department of Paraclinical Sciences, Faculty of Veterinary Science, University of Pretoria, Onderstepoort 0110, South Africa
3
Department of Plant and Soil Sciences, University of Pretoria, Hatfield 0028, South Africa
4
College of Veterinary Medicine, Animal Resources and Biosecurity, Makerere University, Kampala 00256, Uganda
5
Future Africa, University of Pretoria, Hatfield 0028, South Africa
6
School of Natural Resources, University of Missouri, Columbia, MO 65211, USA
7
College of Pharmacy, JSS Academy of Higher Education and Research, Mysuru, Karnataka 570015, India
*
Author to whom correspondence should be addressed.
Plants 2020, 9(6), 753; https://doi.org/10.3390/plants9060753
Received: 13 April 2020 / Revised: 20 May 2020 / Accepted: 23 May 2020 / Published: 15 June 2020
(This article belongs to the Special Issue Medicinal Plants)
Kigelia africana has been used in the management of human ailments since time immemorial. Ethnobotanists have documented the traditional uses of K. africana, which include treatment of skin disorders, cancer and gynecological complaints, among others. This has interested scientists, who have examined K. africana plant parts for their bioactivity. This review provides an insightful understanding on the ethnobotany, phytochemistry and pharmacology of K. africana. Web search engines Google and Google Scholar, as well as the databases of PubMed, Scopus, JSTOR, HINARI, SID, AJOL and Springer Link, were exhaustively searched using key words and phrases. Institutional reports and conference papers were also consulted. A total of 125 relevant international literature sources meeting the inclusion criteria were included. Kigelia africana has biologically active phytochemicals, many of which have been isolated. Whilst the fruits are most often cited in pharmacological studies, other plant parts are also used in herbal preparations. Commercially available products have been formulated from K. africana, though many have not been fully standardized. Despite many efforts by researchers to scientifically validate traditional uses of K. africana, many remain merely claims, thus the need to conduct more research, scientifically validate other traditional uses, isolate new bioactive phytochemicals and standardize K. africana products. View Full-Text
Keywords: Kigelia africana; phytochemistry; traditional uses; pharmacological activity; Bignoniaceae Kigelia africana; phytochemistry; traditional uses; pharmacological activity; Bignoniaceae
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MDPI and ACS Style

Nabatanzi, A.; M. Nkadimeng, S.; Lall, N.; Kabasa, J.D.; J. McGaw, L. Ethnobotany, Phytochemistry and Pharmacological Activity of Kigelia africana (Lam.) Benth. (Bignoniaceae). Plants 2020, 9, 753.

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