Next Article in Journal / Special Issue
Ethnopharmacology, Chemistry and Biological Properties of Four Malian Medicinal Plants
Previous Article in Journal
An Improved Syringe Agroinfiltration Protocol to Enhance Transformation Efficiency by Combinative Use of 5-Azacytidine, Ascorbate Acid and Tween-20
Article Menu
Issue 1 (March) cover image

Export Article

Open AccessCommunication
Plants 2017, 6(1), 10;

Caffeoylquinic Acids from the Aerial Parts of Chrysanthemum coronarium L.

College of Agronomy, Jiangxi Agricultural University, Nanchang 330045, China
Collaborative Innovation Center of Post-Harvest Key Technology and Quality Safety of Fruits and Vegetables in Jiangxi Province, Jiangxi Agricultural University, Nanchang 330045, China
Author to whom correspondence should be addressed.
Academic Editor: Milan S. Stankovic
Received: 6 January 2017 / Revised: 7 February 2017 / Accepted: 9 February 2017 / Published: 17 February 2017
(This article belongs to the Special Issue Medicinal Plants and Natural Product Research)
Full-Text   |   PDF [1690 KB, uploaded 17 February 2017]   |  


To elucidate the chemical compositions of the aerial parts of Chrysanthemum coronarium L., the ethanol extracts of Ch. coronarium L. were firstly isolated by the MCI-gel resin column. The caffeoylquinic acid-rich fractions were further purified by various chromatographic columns including silica gel, Sephadex LH-20, and semi-preparative HPLC to yield the compounds. The purified compounds were characterized by 1H-Nuclear Magnetic Resonance (1H-NMR), 13C-NMR, and high resolution electrospray ionisation mass spectral (HR-ESI-MS) spectroscopy. Seven caffeoylquinic acid (CQA) compounds were isolated from this plant. Their structures were clarified by spectrometric methods and identified as 3-O-caffeoylquinic acid (1), 5-O-caffeoylquinic acid (2), 4-O-caffeoylquinic acid (3), 3,4-di-O-caffeoylquinic acid (4), 1,5-di-O-caffeoylquinic acid (5), 3,5-di-O-caffeoylquinic acid (6), and 4,5-di-O-caffeoylquinic acid (7). Caffeoylquinic acids were the major constituents present in the aerial parts of Ch. coronarium L. All of the isolates except for compounds 2 and 6 were reported for the first time from this species. Moreover, compounds 35, and 7 were identified from the Chrysanthemum genus for the first time. View Full-Text
Keywords: Chrysanthemum coronarium L.; aerial parts; caffeoylquinic acids Chrysanthemum coronarium L.; aerial parts; caffeoylquinic acids

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Share & Cite This Article

MDPI and ACS Style

Wan, C.; Li, S.; Liu, L.; Chen, C.; Fan, S. Caffeoylquinic Acids from the Aerial Parts of Chrysanthemum coronarium L.. Plants 2017, 6, 10.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics



[Return to top]
Plants EISSN 2223-7747 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top