Current Situation and Perspectives of Fruit Annonaceae in Mexico: Biological and Agronomic Importance and Bioactive Properties

Round 1

Reviewer 1 Report

It is opinion of the reviewer that this interesting and well prepared paper before acceptance Leeds several corrections. My individual comments are listed below.

 

20 – What does it mean “chemical properties”? Correction is needed.

Page 3 A map with the geographical distribution of Annonaceae should be completed.

219 – It should be “edible parts” instead of “edible portion”.

Table 1 – It should be :Lipids” instead of “Fat”.

Table 1 – In footnote, explanation of “ND” is needed.

232 – It should be “secondary metabolites/bioactive compounds”.

249 - – It should be “phenolic acids” instead of “simple phenolic compounds”.should be reported in two separated tables.

263 - The chemical structure of cyclopeptides should be described.

Phenolic compounds and fatty acids

Table 2 – The unit (μg/g dw) should be located in the “Content” column.

Table 2 – For leaf – Firs should be listed all the phenolic acids, then flavonoids.

Table 2 – For the names of flavonoids, “-O-“ must be written with italic.

Table 3 – The chemical names must be written with lower case letters.

248 – The chemical structure of acetogenins should be described.

301 – How the extracts were obtaine?

Table 4 – 85 nM means “85 nmol/L” this is concentration not a dose.

Table 4 – for A. cherimola steam bark, it should be “Ethanolic extract”.

15 – It should be “Ethanolic extract” not “Ethanolic extracts”.

325 – “to protect …characteristics” – wrong sentence.

328 – It should be “technologies” instead of “methodologies”/

345 – It should be “1-methylcyclopropane”.

Table 4 – A term of “treatment should be added to technology#1, 5, 9.

Author Response

Please see the attachment.

Author Response File: Author Response.docx

Reviewer 2 Report

The paper presents current situation and perspectives of fruit Annonaceae in Mexico, their biological and agronomic importance and properties. In the last years, interest in these fruit  has increased mainly due to their chemical properties and application in the treatment of human diseases. However, at present much of the basic agronomic information, postharvest handling of the fruits and their potential as new crops for areas with poor soils in organic matter is unknown. The review is interesting, however there are some points that need to be clarified or modified before publication.

1) The Authors provided too few keywords.

2) Introduction is too long and should be shortened.

3) Organization of the manuscript is wrong. It should be prepared according to “Instructions for Authors”. There are a lot of typos and errors in the article. Latin names of plant species should be written in italics (e.g. line 206: Annona squamosa L.). Information about Author contributions, sources of funfing, conflicts of interest e.t.c. are necessery.

4) Many items in the literature are out of date. Please, supplement the Refrerences with new scientific reports.

5) Authors should familiarize themselves with the proper format for References and make appropriate corrections.

Author Response

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Author Response File: Author Response.docx

Reviewer 3 Report

The manuscript from Fuentes et al reviews the literature on the Annona genus an under-utilised fruit-bearing plant. The review collects information on the horticulture of the plants and the phytochemicals they produce. The results of some biological assays are collected as well. The manuscript appears to comprehensively summarize the literature and should be a useful resource for those working with this genus. My only criticism is the English needs some impreovement. Some suggested corrections are listed below.

 

line 22   replace "theme" with "them"

line 29   Needs to be reworded. "the importance of these species knowledge is scarce" does not make sense

line 34  replace "angiosperms, using" with angiosperms. Using"

line 43   replace ". Which" with ", which"

line 51   replace "Dunal," with "Dunal),"

line 56   delete "for"

line 59   replace "America, unlike" with "America. Unlike"

line 61   replace "being Spain" with "Spain being"

line 65   replace "surface, it" with "surface. It"

line 70   replace development, both" with "development. Both"

line 93   replace "beverages desserts" with "beverages, desserts"

line 102   replace "highlighting" with "and"

line 101   replace "Bangladesh by" with "Bangladesh, highlighted by"

line 108   replace "loss, the" with "loss. The"

line 115   replace "created, the" with "created. The"

line 127   replace "production, postharvest" with "production, and postharvest"

line 127   replace "and" with "while"

line 134   replace "a larger" with "the largest"

line 137   replace "generalized, more" with "generalized. More"

line 144   replace "diseases" with "disease"

line 153   Needs to be reworded. Its not clear what has been characterized and who has registered genotypes.

line 168   replace "shores" with "edge" or "verge"

line 171   replace "known, its" with "known. Its"

line 175   replace "in order to" with "for"

line 176   replace "cultivation, it" with "cultivation. It"

line 185   replace "areas, it" with "areas. It"

line 188   replace "cultivation, it" with "cultivation. It"

line 190   replace "season, it" with "season. It"

line 196   italicize "A. squamosa"

line 196   replace "an area" with "a cultivated area"

line 197   replace "tons, its" with "tons. Its"

line 207   replace "warm climates, semi-dry" with "warm, semi-dry climates"

line 210   replace "nutrimental" with "nutritional"

line 214   replace "Besides, the" with "The"

Table 1   replace "Cooper" with "Copper"

Table 1   the Vitamin E entry for A. squamosa is missing

line 224   replace "in the traditional" with "in traditional"

line 225   replace "have been consumed" with "have consumed"

line 227   replace "beverages have" with "of beverages has"

line 227   replace "decoctions or infusions" with "decoction or infusion"

line 228   replace "considering many health benefits such as: parasitic," with "for the treatment of illnesses such as parasitic infections,"

line 235   replace "screening of" with "identified in"

lines 243 and 244 need to be revised. These lines state that "A. muricata pulp ... has the highest diversity of phenolic compounds", but in Table 2 there are more compounds listed from the peel, leaf and seed. Nearly all of the compounds found in the peel have greater concentrations than in the pulp.

line 251   replace "as" with "are"

line 253   replace "Respect to fatty acids the seeds from fruit Annona" with " The seeds from Annona fruit"

line 253   replace "by" with "for"

line 257   replace "contributed" with "contribute"

line 258   replace "also" with "and"

line 264   replace "much interesting since of the point of view pharmaceutical" with "been of much pharmaceutical interest"

line 264   replace "Have been extracted and identified Annomuricin A-C" with "Annomuricin A-C has been extracted and identified"

line 265   replace "Others two" with "Two other"

lines 267,268   replace "have a special attention by their remarkable variety of cyclopeptide derivates" with "show a remarkable variety of derivatives"

line 283   replace "interesting" with "interest"

line 287   replace "to exist" with "there are"

line 289   replace "to" with "at"

line 290   replace "find" with "be found"

line 293   replace "While" with "In"

line 301   replace "principal fruit Annonas" with "Annona's plant parts"

line 307   replace "with" with "to"

line 314   replace "ad" with "and"

line 345   which hormone is being discussed here"?

line 363   replace "paraments" with "parameters"

line 366   replace "Tovar et al. It was" with "Tovar et al was"

line 371   What is meant by "stay"?

line 378   replace "noted, the author" with "noted. The author"

line 379   replace "1- and formulation 3" with "formulations 1 and 3"

line 382   replace "improvement" with "extend the shelf"

line 385   replace "The" with "Because the"

line 386   replace "condition" with "conditions"

line 392   replace "shores" with "verges"

line 397   replace "looking " with "to look"

line 399   replace ". ." with "."

line 401   replace "for" with "for the"

line 404   replace "expand" with "expanding"

line 405   replace "few" with "less"

lines 406-426 The example text in these lines needs to be replaced with the appropriate information.

 

Author Response

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Author Response File: Author Response.docx