Next Article in Journal
Comparative Geometrical Analysis of Leucine-Rich Repeat Structures in the Nod-Like and Toll-Like Receptors in Vertebrate Innate Immunity
Next Article in Special Issue
Splicing Regulation of Pro-Inflammatory Cytokines and Chemokines: At the Interface of the Neuroendocrine and Immune Systems
Previous Article in Journal
Targeting the Checkpoint to Kill Cancer Cells
Previous Article in Special Issue
Chromatin Remodeling and Transcriptional Control in Innate Immunity: Emergence of Akirin2 as a Novel Player
Open AccessReview

Macrophage Expression of Inflammatory Genes in Response to EMCV Infection

Department of Biochemistry, Medical College of Wisconsin, 8701 W. Watertown Plank Rd, Milwaukee, WI 53226, USA
Author to whom correspondence should be addressed.
Academic Editor: Ivana Vancurova
Biomolecules 2015, 5(3), 1938-1954;
Received: 16 June 2015 / Revised: 6 August 2015 / Accepted: 8 August 2015 / Published: 18 August 2015
(This article belongs to the Special Issue Transcriptional Regulation of Pro-Inflammatory Genes)
The expression and production of type 1 interferon is the classic cellular response to virus infection. In addition to this antiviral response, virus infection also stimulates the production of proinflammatory mediators. In this review, the pathways controlling the induction of inflammatory genes and the roles that these inflammatory mediators contribute to host defense against viral pathogens will be discussed. Specific focus will be on the role of the chemokine receptor CCR5, as a signaling receptor controlling the activation of pathways leading to virus-induced inflammatory gene expression. View Full-Text
Keywords: inflammation, cytokine, virus, macrophage, diabetes, Ccr5 inflammation, cytokine, virus, macrophage, diabetes, Ccr5
Show Figures

Figure 1

MDPI and ACS Style

Shaheen, Z.R.; Corbett, J.A. Macrophage Expression of Inflammatory Genes in Response to EMCV Infection. Biomolecules 2015, 5, 1938-1954.

Show more citation formats Show less citations formats

Article Access Map by Country/Region

Only visits after 24 November 2015 are recorded.
Search more from Scilit
Back to TopTop