Biological Evaluation of the Osteoinductive Potential of Dry Teeth after Chemical Demineralization Treatment Using the Tooth Transformer Device
Abstract
:1. Introduction
2. Materials and Methods
2.1. Sample Preparation
2.2. Reagents
2.3. Western Blot Analysis
2.4. Measurement of BMP-2 and Collagen Type 1
2.5. Statistical Analysis
3. Results
3.1. Evaluation of Type I Collagen Content and BMP-2 Protein
3.2. Evaluation of Mineralization Protein LIM-1 (LMP-1) and Transforming Growth Factor-β (TGF-β)
4. Discussion
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
Abbreviations
References
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Title 1 | pg/mL |
---|---|
COL-I | 3.64 ± 1.78 |
BMP-2 | 0.60 ± 0.48 |
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Franceschelli, S.; Lagioia, R.; De Cecco, F.; Minetti, E.; Ballini, A.; Panella, V.; Speranza, L.; Grilli, A.; Mastrangelo, F. Biological Evaluation of the Osteoinductive Potential of Dry Teeth after Chemical Demineralization Treatment Using the Tooth Transformer Device. Biomolecules 2023, 13, 1727. https://doi.org/10.3390/biom13121727
Franceschelli S, Lagioia R, De Cecco F, Minetti E, Ballini A, Panella V, Speranza L, Grilli A, Mastrangelo F. Biological Evaluation of the Osteoinductive Potential of Dry Teeth after Chemical Demineralization Treatment Using the Tooth Transformer Device. Biomolecules. 2023; 13(12):1727. https://doi.org/10.3390/biom13121727
Chicago/Turabian StyleFranceschelli, Sara, Rosalba Lagioia, Federica De Cecco, Elio Minetti, Andrea Ballini, Valeria Panella, Lorenza Speranza, Alfredo Grilli, and Filiberto Mastrangelo. 2023. "Biological Evaluation of the Osteoinductive Potential of Dry Teeth after Chemical Demineralization Treatment Using the Tooth Transformer Device" Biomolecules 13, no. 12: 1727. https://doi.org/10.3390/biom13121727