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DNA-Directed Assembly of Carbon Nanotube–Protein Hybrids

Department of Chemistry, Queen Mary University of London, London E1 4NS, UK
Molecular Biosciences Division, School of Biosciences, Cardiff University, Cardiff CF10 3AX, UK
Authors to whom correspondence should be addressed.
Academic Editor: Carole Aimé
Biomolecules 2021, 11(7), 955;
Received: 13 May 2021 / Revised: 17 June 2021 / Accepted: 18 June 2021 / Published: 29 June 2021
(This article belongs to the Special Issue Bionanocomposites)
Here, we report the controlled assembly of SWCNT–GFP hybrids employing DNA as a linker. Two distinct, enriched SWCNTs chiralities, (6,5), (7,6), and an unsorted SWCNT solution, were selectively functionalized with DNA and hybridized to a complementary GFPDNA conjugate. Atomic force microscopy images confirmed that GFP attachment occurred predominantly at the terminal ends of the nanotubes, as designed. The electronic coupling of the proteins to the nanotubes was confirmed via in-solution fluorescence spectroscopy, that revealed an increase in the emission intensity of GFP when linked to the CNTs. View Full-Text
Keywords: single-walled carbon nanotube; protein; DNA; hybrid; SWCNT; GFP single-walled carbon nanotube; protein; DNA; hybrid; SWCNT; GFP
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MDPI and ACS Style

Freeley, M.; Gwyther, R.E.A.; Jones, D.D.; Palma, M. DNA-Directed Assembly of Carbon Nanotube–Protein Hybrids. Biomolecules 2021, 11, 955.

AMA Style

Freeley M, Gwyther REA, Jones DD, Palma M. DNA-Directed Assembly of Carbon Nanotube–Protein Hybrids. Biomolecules. 2021; 11(7):955.

Chicago/Turabian Style

Freeley, Mark, Rebecca E. A. Gwyther, D. Dafydd Jones, and Matteo Palma. 2021. "DNA-Directed Assembly of Carbon Nanotube–Protein Hybrids" Biomolecules 11, no. 7: 955.

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