Hemorheological and Microcirculatory Relations of Acute Pancreatitis
Abstract
:1. Introduction
2. A Brief Overview of the Pathophysiology of Acute Pancreatitis
3. Relation of Hemorheology and Microcirculation
4. Concerning Animal Models of Acute Pancreatitis
5. Altered Hemorheological Factors Influencing Microcirculation in Acute Pancreatitis
6. Therapeutic Approaches Related to Hemorheology and Microcirculation
7. Conclusions
Author Contributions
Funding
Conflicts of Interest
References
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Parameter/Variable | Main Changes | Reference Example | |
---|---|---|---|
Clinical | Experimental | ||
Blood viscosity | Increase (mainly by hemoconcentration, dehydration) | [71,72,73] | [41] |
Plasma viscosity | Increase (depending on fibrinogen, lipoproteins, and triglyceride concentration) | [74,75] | [41] |
Red blood cell deformability (e.g., elongation index) | Impairment * | [35,76] | [28,77,78,79] |
Red blood cell aggregation (e.g., aggregation index) | Enhancement * | [74] | [41,79] |
Microcirculatory parameters (e.g., blood flux unit, perfusion units, functional capillary density) | General deterioration * | [32,42,80] | [18,30,31,32,41,43] |
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Kotan, R.; Peto, K.; Deak, A.; Szentkereszty, Z.; Nemeth, N. Hemorheological and Microcirculatory Relations of Acute Pancreatitis. Metabolites 2023, 13, 4. https://doi.org/10.3390/metabo13010004
Kotan R, Peto K, Deak A, Szentkereszty Z, Nemeth N. Hemorheological and Microcirculatory Relations of Acute Pancreatitis. Metabolites. 2023; 13(1):4. https://doi.org/10.3390/metabo13010004
Chicago/Turabian StyleKotan, Robert, Katalin Peto, Adam Deak, Zsolt Szentkereszty, and Norbert Nemeth. 2023. "Hemorheological and Microcirculatory Relations of Acute Pancreatitis" Metabolites 13, no. 1: 4. https://doi.org/10.3390/metabo13010004