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Lipidomics Issues on Human Positive ssRNA Virus Infection: An Update

1
Analytical Pharmaceutical Chemistry, Department of Medicinal Chemistry, Uppsala University, Husarg. 3, 75123 Uppsala, Sweden
2
Center of Childhood Cancer Center, Children’s Hospital of Philadelphia, Colket Translational Research Center, 3501 Civic Center Blvd, Philadelphia, PA 19104, USA
3
Spanish National Research Council (CSIC), Boecillo’s Technological Park Bureau, Av. Francisco Vallés 8, 47151 Boecillo, Spain
*
Author to whom correspondence should be addressed.
Metabolites 2020, 10(9), 356; https://doi.org/10.3390/metabo10090356
Received: 16 July 2020 / Revised: 24 August 2020 / Accepted: 27 August 2020 / Published: 31 August 2020
(This article belongs to the Special Issue Advances in Lipidomics: Biomedicine, Nutrients and Methodology)
The pathogenic mechanisms underlying the Biology and Biochemistry of viral infections are known to depend on the lipid metabolism of infected cells. From a lipidomics viewpoint, there are a variety of mechanisms involving virus infection that encompass virus entry, the disturbance of host cell lipid metabolism, and the role played by diverse lipids in regard to the infection effectiveness. All these aspects have currently been tackled separately as independent issues and focused on the function of proteins. Here, we review the role of cholesterol and other lipids in ssRNA+ infection. View Full-Text
Keywords: lipidomics; ssRNA+ virus; membrane fusion; lipid metabolism; cholesterol; sphingolipids; phosphatidylinositol; SARS-CoV lipidomics; ssRNA+ virus; membrane fusion; lipid metabolism; cholesterol; sphingolipids; phosphatidylinositol; SARS-CoV
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MDPI and ACS Style

Balgoma, D.; Gil-de-Gómez, L.; Montero, O. Lipidomics Issues on Human Positive ssRNA Virus Infection: An Update. Metabolites 2020, 10, 356. https://doi.org/10.3390/metabo10090356

AMA Style

Balgoma D, Gil-de-Gómez L, Montero O. Lipidomics Issues on Human Positive ssRNA Virus Infection: An Update. Metabolites. 2020; 10(9):356. https://doi.org/10.3390/metabo10090356

Chicago/Turabian Style

Balgoma, David, Luis Gil-de-Gómez, and Olimpio Montero. 2020. "Lipidomics Issues on Human Positive ssRNA Virus Infection: An Update" Metabolites 10, no. 9: 356. https://doi.org/10.3390/metabo10090356

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