Phytochemistry and Evidence-Based Traditional Uses of the Genus Achillea L.: An Update (2011&ndash;2021)

Barda, Christina; Grafakou, Maria-Eleni; Tomou, Ekaterina-Michaela; Skaltsa, Helen

doi:10.3390/scipharm89040050

Submit to this Journal Review for this Journal Edit a Special Issue

Article Menu

...

Open AccessReview

Phytochemistry and Evidence-Based Traditional Uses of the Genus Achillea L.: An Update (2011–2021)

Christina Barda

Maria-Eleni Grafakou

Ekaterina-Michaela Tomou

and

Helen Skaltsa

Department of Pharmacognosy & Chemistry of Natural Products, Faculty of Pharmacy, School of Health Sciences, National & Kapodistrian University of Athens, Panepistimiopolis, Zografou, 15771 Athens, Greece

Author to whom correspondence should be addressed.

Academic Editor: Roman B. Lesyk

Sci. Pharm. 2021, 89(4), 50; https://doi.org/10.3390/scipharm89040050

Received: 24 October 2021 / Revised: 15 November 2021 / Accepted: 18 November 2021 / Published: 22 November 2021

(This article belongs to the Special Issue Feature Papers in Scientia Pharmaceutica)

View Full-Text Download PDF

Browse Figure

Citation Export

Abstract

Knowledge within the field of phytochemistry research has accelerated at a tremendous speed. The excess of literature reports featuring plants of high ethnopharmacological importance, in combination with our interest in the Asteraceae family and traditional medicine, led us to acknowledge the value of the Achillea L. genus. In a broad context, the various Achillea species are used around the globe for the prevention and treatment of different diseases, including gastrointestinal problems, haemorrhages, pneumonia, rheumatic pains, diuresis, inflammation, infections, and wounds, as well as menstrual and gynaecologic abnormalities. The present review aims to provide and summarize the recent literature (2011–2021) on the phytochemistry of the Achillea genus. In parallel, this study attempts to bridge the reports on the traditional uses with modern pharmacological data. Research articles that focused on secondary metabolites, traditional uses and pharmacological activities were collected from various scientific databases such as Pubmed, ScienceDirect, Reaxys and Google Scholar. This study revealed the presence of 141 phytochemicals, while 24 traditionally used Achillea spp. were discussed in comparison to current data with an experimental basis. View Full-Text

Keywords: Achillea spp.; phytochemicals; flavonoids; sesquiterpene lactones; pharmacological activities; traditional uses

▼ Show Figures

Graphical abstract

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited

Supplementary Material

Supplementary File 1:
ZIP-Document (ZIP, 352 KiB)

Share and Cite

MDPI and ACS Style

Barda, C.; Grafakou, M.-E.; Tomou, E.-M.; Skaltsa, H. Phytochemistry and Evidence-Based Traditional Uses of the Genus Achillea L.: An Update (2011–2021). Sci. Pharm. 2021, 89, 50. https://doi.org/10.3390/scipharm89040050

AMA Style

Barda C, Grafakou M-E, Tomou E-M, Skaltsa H. Phytochemistry and Evidence-Based Traditional Uses of the Genus Achillea L.: An Update (2011–2021). Scientia Pharmaceutica. 2021; 89(4):50. https://doi.org/10.3390/scipharm89040050

Chicago/Turabian Style

Barda, Christina, Maria-Eleni Grafakou, Ekaterina-Michaela Tomou, and Helen Skaltsa. 2021. "Phytochemistry and Evidence-Based Traditional Uses of the Genus Achillea L.: An Update (2011–2021)" Scientia Pharmaceutica 89, no. 4: 50. https://doi.org/10.3390/scipharm89040050

Find Other Styles

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Metrics

Abstract views Pdf views Html views

Article Menu

Phytochemistry and Evidence-Based Traditional Uses of the Genus Achillea L.: An Update (2011–2021)

Abstract

Supplementary Material

Share and Cite

Article Metrics

Article Access Statistics

Article Access Map by Country/Region

Further Information

Guidelines

MDPI Initiatives

Follow MDPI