Examination of High Pressure Micro Systems by μPIV and CFD Simulations Regarding Abrasion, Particle Deposition and Stress Fields

T. GOTHSCH; S. BEINERT; J. H. FINKE; C. LESCHE; S. BÜTTGENBACH; C. MÜLLER-GOYMANN; A. KWADE

doi:10.3797/scipharm.cespt.8.PMS32

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Conference Report

12 July 2010

Examination of High Pressure Micro Systems by μPIV and CFD Simulations Regarding Abrasion, Particle Deposition and Stress Fields

and

Institute for Particle Technology, Technische Universität Braunschweig, Braunschweig, Germany

Institute for Pharmaceutical Technology, Technische Universität Braunschweig, Braunschweig, Germany

Institute for Microtechnology, Technische Universität Braunschweig, Braunschweig, Germany

Author to whom correspondence should be addressed.

Sci. Pharm.2010, 78(3), 659;https://doi.org/10.3797/scipharm.cespt.8.PMS32

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Abstract

The dispersion and emulsification in micro channels by high pressure have several characteristics which recommend these methods especially for pharmaceutical applications, e. g. the possibility to use very small educt batches, a narrow residence time distribution and a relatively accurate adjustment of the induced stresses with a good reproducibility. [...]

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