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Acknowledgement to Reviewers of Cosmetics in 2019
Open AccessArticle

The Potential Application of Ecklonia cava Extract in Scalp Protection

Biospectrum Life Science Institute, U-TOWER 18th FL, 767, Sinsu Ro, Suji Gu, Yongin City, Gyunggi Do 16827, Korea
Author to whom correspondence should be addressed.
Cosmetics 2020, 7(1), 9;
Received: 17 December 2019 / Revised: 16 January 2020 / Accepted: 17 January 2020 / Published: 20 January 2020
The scalp is exposed to environmental hazards including airborne pollutants, which exert adverse effects on skin health. Therefore, compounds for defending skin from pollutants have attracted interest in the cosmeceutical community. We investigated whether Ecklonia cava exhibited prophylactic effects against urban pollutants by measuring cell viability and cell cycle distribution in human follicle dermal papilla cells (HFDPC). The effect of E. cava on pollutant-induced damage to skin barrier was determined by measuring filaggrin and MMP-1 expression in both keratinocytes and in a skin explant model. In a clinical trial, the effect of E. cava on scalp skin of patients with scalp scale was observed by evaluating hydration and redness after 4 weeks of daily treatment with a shampoo containing E. cava extract. E. cava extract recovered the loss of cell viability and abnormal cell cycle distribution induced by urban pollutants in HFDPCs. It also attenuated pollutant-induced damage to skin barrier by decreasing MMP-1 and increasing filaggrin expression in keratinocytes and the epidermis of skin explants. Moreover, E. cava showed soothing effects on human scalp by increasing hydration and decreasing redness in a clinical trial. Collectively, E. cava extract may be a good candidate for therapeutic applications designed to repair or protect hair scalp. View Full-Text
Keywords: Ecklonia cava; scalp; urban dust; hydration; anti-inflammation Ecklonia cava; scalp; urban dust; hydration; anti-inflammation
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Kim, H.; Woo, H.; Shin, S.; Park, D.; Jung, E. The Potential Application of Ecklonia cava Extract in Scalp Protection. Cosmetics 2020, 7, 9.

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