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Cosmetics 2018, 5(4), 66; https://doi.org/10.3390/cosmetics5040066

Biocellulose Masks as Delivery Systems: A Novel Methodological Approach to Assure Quality and Safety

1
Department of Drug Sciences, University of Pavia, 27100 Pavia, Italy
2
Etichub s.r.l, Academic Spin-Off of Pavia University, 27100 Pavia, Italy
3
ASST Papa Giovanni XXIII, 24127 Bergamo, Italy
4
iBeauty, Brembate di Sopra, 24030 Bergamo, Italy
*
Author to whom correspondence should be addressed.
Received: 22 July 2018 / Revised: 30 September 2018 / Accepted: 31 October 2018 / Published: 9 November 2018
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Abstract

Bacterial cellulose (BC) has become of great interest in recent years, as a delivery system in several areas of application, including food, drugs, and cosmetics, thanks to its exclusive advantages, such as high biocompatibility, water holding capacity, and good gas permeability. The novel approach of the authors has led to a protocol for checking the quality and safety of bacterial cellulose matrices in the manufacture of cosmetic masks. Two non-destructive techniques, near-infrared spectroscopy (NIR) and multiple light scattering (MLS), were used to verify different parameters affecting the quality of BC sheets, allowing cellulose masks to be checked over time. NIR spectroscopy allowed for discovering changes in the water content, depending on filling/packaging procedures, like flat-folding. Multiple light scattering was used to ascertain the stability of solutions in contact with masks. From a clinical standpoint, the cutaneous tolerability of biocellulose masks, and their effect on skin parameters, were evaluated through some specific “in vivo” tests. Also, a safety evaluation during application was conducted through different studies: a short-term one after single application, and a long-term one upon continued use. View Full-Text
Keywords: bacterial cellulose; tolerability evaluation; stability; NIR spectroscopy; multiple light scattering; skin parameters bacterial cellulose; tolerability evaluation; stability; NIR spectroscopy; multiple light scattering; skin parameters
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
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MDPI and ACS Style

Perugini, P.; Bleve, M.; Cortinovis, F.; Colpani, A. Biocellulose Masks as Delivery Systems: A Novel Methodological Approach to Assure Quality and Safety. Cosmetics 2018, 5, 66.

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