Next Article in Journal
Anti-Aging Efficacy of Melatonin-Based Cream: Clinical and Instrumental Skin Evaluation
Next Article in Special Issue
Endocrine Disruption by Mixtures in Topical Consumer Products
Previous Article in Journal / Special Issue
Agro-Industrial By-Products and Their Bioactive Compounds—An Ally against Oxidative Stress and Skin Aging
Article Menu

Export Article

Open AccessFeature PaperArticle
Cosmetics 2018, 5(4), 59; https://doi.org/10.3390/cosmetics5040059

Formulating O/W Emulsions with Plant-Based Actives: A Stability Challenge for an Effective Product

1
Department of Pharmaceutical and Pharmacological Sciences, University of Padova, Via Francesco Marzolo 5, 35131 Padova, Italy
2
UniR&D srl, Spin-Off University of Padova, Via Niccolò Tommaseo 69, 35131 Padova, Italy
3
Vitroscreen srl, P.le Giulio Cesare 17, 20145 Milan, Italy
4
INDENA S.p.A., Viale Ortles 12, 20139 Milan, Italy
5
UNIFARCO S.p.A., Via Cal Longa 62, 32035 Santa Giustina (BL), Italy
*
Author to whom correspondence should be addressed.
Received: 6 September 2018 / Revised: 27 September 2018 / Accepted: 2 October 2018 / Published: 9 October 2018
(This article belongs to the Special Issue Green Ingredients in Cosmetics and food)
Full-Text   |   PDF [3233 KB, uploaded 9 October 2018]   |  

Abstract

Quality, safety, and efficacy concerns added to instability, poor absorption, and the dispersion of actives are common problems while formulating plant-based cosmetics. Furthermore, a correct balance between the stability of the emulsion, the sensory profile, and the high efficacy has to be considered to formulate an effective product. In this paper, we demonstrate that rheology is a methodological tool that can be used while designing a new product. In particular, we developed an O/W emulsion which is easy to spread on irritated skin, and that can soothe the redness and discomfort caused by the exposure to both physical and chemical irritating agents. The green active mixture consists of three natural raw materials: Bosexil®, Zanthalene®, and Xilogel®. Each ingredient has a well-demonstrated efficacy in terms of soothing, anti-itching, and moisturizing properties respectively. Starting from the selection of a new green emulsifying system, through the analysis of the rheological properties, we obtained a stable and easy-to-apply o/w emulsion. The efficacy of the optimized product was assessed in vitro on intact and injured skin using the SkinEthic™ Reconstituted Human Epidermis (RHE) as a biological model. View Full-Text
Keywords: rheology; plant-based actives; emulsion design rheology; plant-based actives; emulsion design
Figures

Graphical abstract

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
SciFeed

Share & Cite This Article

MDPI and ACS Style

Semenzato, A.; Costantini, A.; Meloni, M.; Maramaldi, G.; Meneghin, M.; Baratto, G. Formulating O/W Emulsions with Plant-Based Actives: A Stability Challenge for an Effective Product. Cosmetics 2018, 5, 59.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Cosmetics EISSN 2079-9284 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top