Author Contributions
Conceptualization, S.Y. and X.J.Y.; methodology, L.L.-D.; data curation, L.L.-D.; writing-original draft, L.L.-D.; writing—review and editing, L.L.-D.; project administration, S.Y.; supervision, X.J.Y. All authors have read and agreed to the published version of the manuscript.
Figure 1.
Structure of DEGDMA, IBOA, and HEMA.
Figure 1.
Structure of DEGDMA, IBOA, and HEMA.
Figure 2.
Cardboard stand with polyester substrate outlined to duplicate the finger guide of the OPI Starlight lamp.
Figure 2.
Cardboard stand with polyester substrate outlined to duplicate the finger guide of the OPI Starlight lamp.
Figure 3.
Example of gas chromatography with flame-ionization detector chromatogram of 29.8 ppm of DEGDMA (section from 7.00 min to 9.00 min, DEGDMA peak is at 7.85 min).
Figure 3.
Example of gas chromatography with flame-ionization detector chromatogram of 29.8 ppm of DEGDMA (section from 7.00 min to 9.00 min, DEGDMA peak is at 7.85 min).
Figure 4.
Example of gas chromatography with flame-ionization detector chromatogram of 67.5 ppm working standard of IBOA (section from 11.40 min to 13.40 min, IBOA peak is at 12.42 min).
Figure 4.
Example of gas chromatography with flame-ionization detector chromatogram of 67.5 ppm working standard of IBOA (section from 11.40 min to 13.40 min, IBOA peak is at 12.42 min).
Figure 5.
Example of gas chromatography with flame-ionization detector chromatogram of 22.9 ppm HEMA (section from 2.00 min to 5.00 min, HEMA peak is at 2.97 min).
Figure 5.
Example of gas chromatography with flame-ionization detector chromatogram of 22.9 ppm HEMA (section from 2.00 min to 5.00 min, HEMA peak is at 2.97 min).
Figure 6.
Calibration curve example for DEGDMA, IBOA, and HEMA.
Figure 6.
Calibration curve example for DEGDMA, IBOA, and HEMA.
Figure 7.
Chromatogram of DEGDMA peak at 7.85 min found in a commercially available product.
Figure 7.
Chromatogram of DEGDMA peak at 7.85 min found in a commercially available product.
Figure 8.
Chromatogram of IBOA peak at 12.42 min found in a commercially available product.
Figure 8.
Chromatogram of IBOA peak at 12.42 min found in a commercially available product.
Figure 9.
Chromatogram of HEMA peak at 2.97 min found in a commercially available product.
Figure 9.
Chromatogram of HEMA peak at 2.97 min found in a commercially available product.
Figure 10.
GC-FID chromatogram of DEGDMA found in a commercially available product film.
Figure 10.
GC-FID chromatogram of DEGDMA found in a commercially available product film.
Figure 11.
GC-FID chromatogram of IBOA found in a commercially available product film.
Figure 11.
GC-FID chromatogram of IBOA found in a commercially available product film.
Figure 12.
GC-FID chromatogram of HEMA found in a commercially available product film.
Figure 12.
GC-FID chromatogram of HEMA found in a commercially available product film.
Table 1.
Stability of analytes.
Table 1.
Stability of analytes.
Monomer | Solvent | Concentration (µg/mL) | Time | % Loss |
---|
DEGDMA | Acetonitrile | 3.3 | 1 h | 2.4 |
IBOA | Ethanol | 1.3 | 24 h | 2.4 |
HEMA | Methanol | 1.4 | 24 h | 0.9 |
Table 2.
HEMA gradient.
Column | ACE Super-C18, 3.0 µm, 4.6 × 100 mm2, Cat#: 10829-210 (Avantor, VWR)) OR Equivalent |
Mobile phase | A: 0.1% Phosphoric Acid + Water B: Acetonitrile | |
Gradient | Time (min) | B/A |
0 | 25/75 |
4 | 25/75 |
5 | 99/1 |
7 | 99/1 |
8 | 25/75 |
Flow rate (mL/min) | 0.8 |
Detector | UV/Vis |
Wavelength (nm) | 210 |
Scan | 250–400 |
Injection vol. (µL) | 5.0 |
Run Time: (min) | 15 |
Column Temp. (°C) | 25 |
Table 3.
DEGDMA experimental setting for gas chromatography with flame ionization detector measurements.
Table 3.
DEGDMA experimental setting for gas chromatography with flame ionization detector measurements.
GC | Injection volume | 1 µL | | |
| GC-column | Stabilwax 30 m, i.d. 0.25 mm, 0.25 µm coating thickness |
| Purge gas/flow | Helium, 1.59 mL/min | | |
| Temperature program | Rate (°C/min) | Temperature (°C) | Time (min) |
| | | 80 | 0.5 |
| | 25 | 210 | 6 |
| Injector temp. | 270 °C | | |
| Split | 1/10 | | |
FID | Base temperature | 310 °C | | |
| Air flow | 450 mL/min | | |
| Hydrogen flow | 45 mL/min | | |
| Make-up gas flow | 45 mL/min | | |
Table 4.
IBOA experimental setting for gas chromatography with flame ionization detector measurements.
Table 4.
IBOA experimental setting for gas chromatography with flame ionization detector measurements.
GC | Injection volume | 1 µL | | |
| GC-column | Elite 5MS 30 m, i.d. 0.25 mm, 0.25 µm coating thickness |
| Purge gas/flow | Helium, 1.59 mL/min | | |
| Temperature program | Rate (°C/min) | Temperature (°C) | Time (min) |
| | | 40 | 0.5 |
| | 25 | 310 | 2 |
| Injector temperature | 250 °C | | |
| Split | 1/40 | | |
FID | Base temperature | 310 °C | | |
| Air flow | 450 mL/min | | |
| Hydrogen flow | 45 mL/min | | |
| Make-up gas flow | 45 mL/min | | |
Table 5.
Linear calibration equation for each monomer.
Table 5.
Linear calibration equation for each monomer.
Monomer | r2 | Equation |
---|
DEGDMA | 0.999 | Y = 5.12 × 101x + 1.01 × 10−2 |
IBOA | 0.999 | Y = 3.13 × 101x − 4.51 × 10−1 |
HEMA | 1.000 | Y = 2.18 × 104x − 7.03 × 103 |
Table 6.
System precision data for DEGDMA, IBOA, and HEMA.
Table 6.
System precision data for DEGDMA, IBOA, and HEMA.
(No. Replicates) | DEGDMA | IBOA | HEMA |
---|
Peak Area (µV × s) |
---|
1 | 2427.7 | 36.8 | 24,064.0 |
2 | 2442.1 | 36.6 | 24,232.8 |
3 | 2416.8 | 37.4 | 24,256.2 |
4 | 2399.3 | 37.3 | 23,999.8 |
5 | 2356.2 | 36.8 | 24,270.4 |
Average | 2408.4 | 37.0 | 24,164.6 |
Std Dev. | 33.1 | 0.3 | 124.0 |
RSD | 1.4 | 1.0 | 0.5 |
Table 9.
DEGDMA, IBOA, and HEMA percent recoveries.
Table 9.
DEGDMA, IBOA, and HEMA percent recoveries.
(No. Replicates) | DEGDMA | IBOA | HEMA |
---|
Standards | 21.4 ppm | 287.8 ppm | 23.3 ppm | 232.6 ppm | 23.0 ppm | 249.7 ppm |
---|
1 | 100.7 | 96.3 | 101.6 | 99.8 | 101.7 | 99.4 |
2 | 103.1 | 99.3 | 107.3 | 102.5 | 103.1 | 98.7 |
3 | 98.0 | 97.0 | 111.4 | 99.6 | 104.0 | 99.5 |
Average | 100.6 | 97.6 | 106.8 | 100.6 | 102.9 | 99.2 |
Std Dev. | 2.6 | 1.6 | 4.9 | 1.6 | 1.2 | 0.4 |
RSD | 2.6 | 1.6 | 4.6 | 1.6 | 1.1 | 0.4 |
Table 10.
DEGDMA, IBOA, and HEMA repeatability measurements in commercially available bulk samples.
Table 10.
DEGDMA, IBOA, and HEMA repeatability measurements in commercially available bulk samples.
(No. Replicates) | DEGDMA | IBOA | HEMA |
---|
Peak Area (µs) |
---|
1 | 1533.6 | 7775.2 | 2,243,596.6 |
2 | 1473.5 | 8693.3 | 2,292,909.7 |
Average | 1503.6 | 8234.3 | 2,268,253.2 |
Std Dev. | 42.5 | 649.2 | 34,869.7 |
RSD | 2.8 | 7.9 | 1.5 |
Table 11.
Quantitative determination of each monomer found in commercially available bulk samples.
Table 11.
Quantitative determination of each monomer found in commercially available bulk samples.
Product # | Monomer | Amount (%) | % RSD |
---|
1 | DEGDMA | 14.24 | 3.06 |
2 | IBOA | 29.0 | 3.08 |
3 | HEMA | 15.3 | 3.90 |
Table 12.
Residual levels of the monomers found in gel films of commercial products.
Table 12.
Residual levels of the monomers found in gel films of commercial products.
Product # | Monomer | Amount (µg/g) |
---|
1 | DEGDMA | 800 |
2 | IBOA | 56 |
3 | HEMA | 139 |