Next Article in Journal
Chitosan/Thyme Oil Systems as Affected by Stabilizing Agent: Physical and Antimicrobial Properties
Next Article in Special Issue
Chitosan Cross-Linked Bio-based Antimicrobial Polypropylene Meshes for Hernia Repair Loaded with Levofloxacin HCl via Cold Oxygen Plasma
Previous Article in Journal
Thermochromic Behavior of VO2/Polymer Nanocomposites for Energy Saving Coatings
Previous Article in Special Issue
Designing a Laboratory Bioassay for Evaluating the Efficacy of Antifouling Paints on Amphibalanus amphitrite Using a Flow-Through System
Article Menu
Issue 3 (March) cover image

Export Article

Open AccessArticle
Coatings 2019, 9(3), 164;

Polydopamine-Inspired Surface Modification of Polypropylene Hernia Mesh Devices via Cold Oxygen Plasma: Antibacterial and Drug Release Properties

College of Textiles and Fashion, Xinjiang University, 666 Sheng Li Road, Tian Shan, Wulumuqi 830046, China
Key Laboratory of Textile Science and Technology of Ministry of Education, Key Laboratory of Biomedical Textile Materials and Technology in Textile Industry, College of Textiles, Donghua University, 2999 North Renmin Road, Songjiang, Shanghai 201620, China
Department of Textile Engineering, Mehran University of Engineering and Technology, Jamshoro, Sindh 76062, Pakistan
Department of Surgery, University of Laval, Quebec, QC G1V 0A6, Canada
Authors to whom correspondence should be addressed.
Received: 20 December 2018 / Revised: 22 February 2019 / Accepted: 22 February 2019 / Published: 1 March 2019
(This article belongs to the Special Issue Advances in Antimicrobial Coatings)
Full-Text   |   PDF [5010 KB, uploaded 1 March 2019]   |  


Mesh infection is a major complication of hernia surgery after polypropylene (PP) mesh implantation. Modifying the PP mesh with antibacterial drugs is an effective way to reduce the chance of infection, but the hydrophobic characteristic of PP fibers has obstructed the drug adhesion. Therefore, to prepare antimicrobial PP mesh with a stable drug coating layer and to slow the drug release property during the hernia repair process has a great practical meaning. In this work, PP meshes were coated by bio-inspired polydopamine (PDA), which can load and release levofloxacin. PP meshes were activated with cold oxygen plasma and then plasma activated PP fibers were coated with PDA. The PDA coated meshes were further soaked in levofloxacin. The levofloxacin loaded PP meshes demonstrate excellent antimicrobial properties for 6 days and the drug release has lasted for at least 24 h. Moreover, a control PP mesh sample without plasma treatment was also prepared, after coating with PDA and loading levofloxacin. The antimicrobial property was sustained only for two days. The maximum inhibition zone of PDA coated meshes with and without plasma treatment was 12.5 and 9 mm, respectively. On all accounts, the modification strategy can facilely lead to long-term property of infection prevention. View Full-Text
Keywords: polypropylene; hernia meshes; antibacterial; drug release; polydopamine polypropylene; hernia meshes; antibacterial; drug release; polydopamine

Graphical abstract

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

Share & Cite This Article

MDPI and ACS Style

Saitaer, X.; Sanbhal, N.; Qiao, Y.; Li, Y.; Gao, J.; Brochu, G.; Guidoin, R.; Khatri, A.; Wang, L. Polydopamine-Inspired Surface Modification of Polypropylene Hernia Mesh Devices via Cold Oxygen Plasma: Antibacterial and Drug Release Properties. Coatings 2019, 9, 164.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics



[Return to top]
Coatings EISSN 2079-6412 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top