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Review

Research Progress of the Coatings Fabricated onto Titanium and/or Titanium Alloy Surfaces in Biomaterials for Medical Applications for Anticorrosive Applications

College & Hospital of Stomatology, Anhui Medical University, Key Lab. of Oral Diseases Research of Anhui Province, Hefei 230032, China
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Author to whom correspondence should be addressed.
Coatings 2025, 15(5), 599; https://doi.org/10.3390/coatings15050599 (registering DOI)
Submission received: 25 March 2025 / Revised: 6 May 2025 / Accepted: 12 May 2025 / Published: 17 May 2025
(This article belongs to the Special Issue Innovative Coatings for Corrosion Protection of Alloy Surfaces)

Abstract

Titanium (Ti) and its alloys have attracted more interest, as they are widely employed as biomaterials due to their great biocompatibility, excellent strength ratio, and lightweight. However, corrosion occurs slowly due to an electrochemical reaction once the Ti material has been placed in the human body, contributing to infection and failure of implants in medical applications. Thus, the corrosion phenomenon has caused great concern in the biomedical field. It is desirable to make the surface modification to provide better corrosion resistance. The fabrication techniques of the coatings fabricated onto Ti and/or Ti alloy surfaces have been reported, including sol–gel, annealing, plasma spraying, plasma immersion ion implantation, physical vapor deposition, chemical vapor deposition, anodization, and micro-arc oxidation. This review first describes the corrosion types, including localized corrosion (both pitting and crevice corrosion), galvanic corrosion, selective leaching, stress corrosion cracking (SCC), corrosion fatigue (CF), and fretting corrosion. In the second part, the effects of corrosion on the human body were discussed, and the primary cause for clinical failure and allergies has been identified as the excessive release of poisonous and dangerous metal ions (Co, Ni, and Ti) from corroded implants into bodily fluids. The inclusion and exclusion criteria during the selection of literature are described in the third section. In the last section, we emphasized the current research progress of Ti alloy (particularly Ti6Al4V alloy) coatings in biomaterials for medical applications involving dental, orthopedic, and cardiovascular implants for anticorrosive applications. However, there are also several problems to explore and address in future studies, such as the release of excessive metal ions, etc. This review will draw attention to both researchers and clinicians, which could help to increase the coatings fabricated onto Ti and/or Ti alloy surfaces for anticorrosive applications in biomaterials for medical applications.
Keywords: Ti; Ti alloy; coating; biomaterials; anticorrosive; implant Ti; Ti alloy; coating; biomaterials; anticorrosive; implant

Share and Cite

MDPI and ACS Style

Rao, Q.; Zhang, J.; Chen, Y.; Yang, Y.; Chen, X.; Liu, D.; Zhu, R.; Li, A.; Lv, Y.; Zheng, S. Research Progress of the Coatings Fabricated onto Titanium and/or Titanium Alloy Surfaces in Biomaterials for Medical Applications for Anticorrosive Applications. Coatings 2025, 15, 599. https://doi.org/10.3390/coatings15050599

AMA Style

Rao Q, Zhang J, Chen Y, Yang Y, Chen X, Liu D, Zhu R, Li A, Lv Y, Zheng S. Research Progress of the Coatings Fabricated onto Titanium and/or Titanium Alloy Surfaces in Biomaterials for Medical Applications for Anticorrosive Applications. Coatings. 2025; 15(5):599. https://doi.org/10.3390/coatings15050599

Chicago/Turabian Style

Rao, Qin, Jinshuang Zhang, Yaqing Chen, Yujin Yang, Xu Chen, Donghao Liu, Ruilu Zhu, Ang Li, Yanping Lv, and Shunli Zheng. 2025. "Research Progress of the Coatings Fabricated onto Titanium and/or Titanium Alloy Surfaces in Biomaterials for Medical Applications for Anticorrosive Applications" Coatings 15, no. 5: 599. https://doi.org/10.3390/coatings15050599

APA Style

Rao, Q., Zhang, J., Chen, Y., Yang, Y., Chen, X., Liu, D., Zhu, R., Li, A., Lv, Y., & Zheng, S. (2025). Research Progress of the Coatings Fabricated onto Titanium and/or Titanium Alloy Surfaces in Biomaterials for Medical Applications for Anticorrosive Applications. Coatings, 15(5), 599. https://doi.org/10.3390/coatings15050599

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