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Volume 13
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10.3390/coatings13060977
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Review

Surface Modification Techniques for Polyetheretherketone as Spinal Interbody Fusion Cage Material to Stimulate Biological Response: A Review

by
Shu Liu
1,†,
Junhao Sui
2,†,
Kai Chen
1,†,
Yun Ding
2,
Xinyu Chang
2,
Yijin Hou
3,
Lin Zhang
4,
Xiangyu Meng
2,
Zihao Xu
2,
Licai Miao
2,
Shicheng Huo
5,*,
Guangchao Wang
2,* and
Zhicai Shi
1,*
1
Department of Spine Surgery, Changhai Hospital, Navy Medical University, Shanghai 200433, China
2
Department of Orthopedics, Changhai Hospital, Navy Medical University, Shanghai 200433, China
3
School of Medical Instrument and Food Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China
4
School of Exercise and Health, Shanghai University of Sport, Shanghai 200433, China
5
Department of Orthopedic Surgery, Spine Center, Changzheng Hospital, Navy Medical University, Shanghai 200003, China
*
Authors to whom correspondence should be addressed.
†
These authors contributed equally to this work.
Coatings 2023, 13(6), 977; https://doi.org/10.3390/coatings13060977
Submission received: 24 April 2023 / Revised: 19 May 2023 / Accepted: 21 May 2023 / Published: 24 May 2023
(This article belongs to the Special Issue Application of Coatings on Implants Surfaces)
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Abstract

Currently, spinal interbody cages are crucial for spinal fusion surgeries. Due to the mechanical and imaging characteristics of polyetheretherketone (PEEK), it is a widely used material for cages. However, the bioinert PEEK has poor osseointegration, thereby preventing the ideal fusion of PEEK cages. Therefore, efforts have been made for improving biological activity using surface modification techniques, including physical as well as chemical modifications and surface coating. In this study, we reviewed and analyzed recent studies on PEEK surface modification techniques to enhance our understanding for future studies.
Keywords: polyetheretherketone; surface modification; bioactivity; osseointegration; interbody cage polyetheretherketone; surface modification; bioactivity; osseointegration; interbody cage

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MDPI and ACS Style

Liu, S.; Sui, J.; Chen, K.; Ding, Y.; Chang, X.; Hou, Y.; Zhang, L.; Meng, X.; Xu, Z.; Miao, L.; et al. Surface Modification Techniques for Polyetheretherketone as Spinal Interbody Fusion Cage Material to Stimulate Biological Response: A Review. Coatings 2023, 13, 977. https://doi.org/10.3390/coatings13060977

AMA Style

Liu S, Sui J, Chen K, Ding Y, Chang X, Hou Y, Zhang L, Meng X, Xu Z, Miao L, et al. Surface Modification Techniques for Polyetheretherketone as Spinal Interbody Fusion Cage Material to Stimulate Biological Response: A Review. Coatings. 2023; 13(6):977. https://doi.org/10.3390/coatings13060977

Chicago/Turabian Style

Liu, Shu, Junhao Sui, Kai Chen, Yun Ding, Xinyu Chang, Yijin Hou, Lin Zhang, Xiangyu Meng, Zihao Xu, Licai Miao, and et al. 2023. "Surface Modification Techniques for Polyetheretherketone as Spinal Interbody Fusion Cage Material to Stimulate Biological Response: A Review" Coatings 13, no. 6: 977. https://doi.org/10.3390/coatings13060977

APA Style

Liu, S., Sui, J., Chen, K., Ding, Y., Chang, X., Hou, Y., Zhang, L., Meng, X., Xu, Z., Miao, L., Huo, S., Wang, G., & Shi, Z. (2023). Surface Modification Techniques for Polyetheretherketone as Spinal Interbody Fusion Cage Material to Stimulate Biological Response: A Review. Coatings, 13(6), 977. https://doi.org/10.3390/coatings13060977

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