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Article

Fabrication and Physico-Chemical Properties of Antifungal Samarium Doped Hydroxyapatite Thin Films

1
National Institute of Materials Physics, Atomistilor Street, No. 405A, P.O. Box MG 07, 077125 Magurele, Romania
2
HORIBA FRANCE S.A.S., Boulevard Thomas Gobert, Passage Jobin Yvon, 91120 Palaiseau, France
3
Department of Mechanics, University Politehnica of Bucharest, BN 002, 313 Splaiul Independentei, Sector 6, 060042 Bucharest, Romania
*
Authors to whom correspondence should be addressed.
Academic Editor: Enrico Sassoni
Coatings 2021, 11(12), 1466; https://doi.org/10.3390/coatings11121466
Received: 30 October 2021 / Revised: 24 November 2021 / Accepted: 27 November 2021 / Published: 29 November 2021
(This article belongs to the Special Issue Biomaterials and Antimicrobial Coatings)
Samarium doped hydroxyapatite (Ca10−xSmx(PO4)6(OH)2, xSm = 0.5, 50SmHAp) is a very promising candidate to be used for different coatings in various dental and orthopedic implants. We report, for the first time, the obtaining of 50SmHAp thin films by a cost-effective method, namely spin coating. Thin films of 50SmHAp on silicon substrate have been analyzed by various techniques such as Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), atomic force microscopy (AFM), Metallographic microscopy and Glow Discharge Optical Emission Spectroscopy (GDOES). The stability of 50SmHAp suspension was evaluated by ultrasound measurements. Fourier transform infrared spectroscopy (FTIR), transmission electron microscopy (TEM) and scanning electron microscopy (SEM) were also used to evaluate the 50SmHAp suspension. The antifungal activity of 50SmHAp suspension and coatings was assessed using Candida albicans ATCC 10231 fungal strain (C. albicans). The results of the antifungal assays depicted that both 50SmHAp suspensions and coatings were effective in inhibiting the development of C. albicans fungal cells, thus making them ideal candidates for the development of novel antifungal agents. The obtained results give new perspective for possible applications of 50SmHAp thin films in various medical applications due to their antifungal properties. View Full-Text
Keywords: samarium; hydroxyapatite; spin-coating; coatings; morphology; antifungal assay samarium; hydroxyapatite; spin-coating; coatings; morphology; antifungal assay
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MDPI and ACS Style

Ciobanu, C.S.; Predoi, D.; Chapon, P.; Predoi, M.V.; Iconaru, S.L. Fabrication and Physico-Chemical Properties of Antifungal Samarium Doped Hydroxyapatite Thin Films. Coatings 2021, 11, 1466. https://doi.org/10.3390/coatings11121466

AMA Style

Ciobanu CS, Predoi D, Chapon P, Predoi MV, Iconaru SL. Fabrication and Physico-Chemical Properties of Antifungal Samarium Doped Hydroxyapatite Thin Films. Coatings. 2021; 11(12):1466. https://doi.org/10.3390/coatings11121466

Chicago/Turabian Style

Ciobanu, Carmen Steluta, Daniela Predoi, Patrick Chapon, Mihai Valentin Predoi, and Simona Liliana Iconaru. 2021. "Fabrication and Physico-Chemical Properties of Antifungal Samarium Doped Hydroxyapatite Thin Films" Coatings 11, no. 12: 1466. https://doi.org/10.3390/coatings11121466

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