Properties of Titanium Oxide Coating on MgZn Alloy by Magnetron Sputtering for Stent Application
Abstract
:1. Introduction
2. Materials and Methods
2.1. Preparation of the Coating
2.2. Characterizations
2.3. Corrosion Tests
2.4. Biocompatibility Evaluation
3. Results and Discussion
3.1. Coating Characteristics
3.2. Corrosion Behavior
3.3. Biocompatibility
4. Conclusions
- (1)
- A 400 nm-thick titanium oxide coating with a smooth surface was deposited on the MgZn substrate after 2 h magnetron sputtering at room temperature. The coating was composed of dense amorphous TiO2 nanoparticles.
- (2)
- The corrosion resistance of MgZn alloy was improved apparently by the TiO2 coating. After 14 d of immersion in SBF, the surface of the TiO2-coated sample was less corroded than that of the substrate.
- (3)
- The uncoated Mg alloys caused serious hemolysis and aggregation of platelets, whereas the TiO2-coated sample had a hemolysis ratio of less than 1% and showed a better ability of anti-platelet adhesion. The TiO2-coated MgZn alloy exhibited lower cytotoxicity and the endothelial cells attached well on the surface, indicating good cytocompatibility.
Author Contributions
Funding
Conflicts of Interest
References
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Samples | Hemolysis Ratio (%) | Cell Viability (%) | |
---|---|---|---|
1 d | 3 d | ||
Control | – | 100 | 100 |
Bare MgZn substrate | 47.23 | 94.1 | 89.5 |
MgZn substrate with TiO2 coating | 0.10 | 93.4 | 94.8 |
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Hou, S.; Yu, W.; Yang, Z.; Li, Y.; Yang, L.; Lang, S. Properties of Titanium Oxide Coating on MgZn Alloy by Magnetron Sputtering for Stent Application. Coatings 2020, 10, 999. https://doi.org/10.3390/coatings10100999
Hou S, Yu W, Yang Z, Li Y, Yang L, Lang S. Properties of Titanium Oxide Coating on MgZn Alloy by Magnetron Sputtering for Stent Application. Coatings. 2020; 10(10):999. https://doi.org/10.3390/coatings10100999
Chicago/Turabian StyleHou, Shusen, Weixin Yu, Zhijun Yang, Yue Li, Lin Yang, and Shaoting Lang. 2020. "Properties of Titanium Oxide Coating on MgZn Alloy by Magnetron Sputtering for Stent Application" Coatings 10, no. 10: 999. https://doi.org/10.3390/coatings10100999