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Ophthalmic Nanosystems with Antioxidants for the Prevention and Treatment of Eye Diseases

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Department of Pharmaceutical Technology and Biopharmaceutics, Iuliu Hatieganu University of Medicine and Pharmacy, 41 V. Babes Street, 400012 Cluj-Napoca, Romania
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Department of Pharmacology, Physiology and Physiopathology, Iuliu Hatieganu University of Medicine and Pharmacy, 6 L. Pasteur Street, 400349 Cluj-Napoca, Romania
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Department of Ophthalmology, Iuliu Hatieganu University of Medicine and Pharmacy, 3-5 Clinicilor Street, 400006 Cluj-Napoca, Romania
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Department of Pathophysiology, University of Agricultural Sciences and Veterinary Medicine, 3 Calea Manastur Street, 400374 Cluj-Napoca, Romania
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Department of Analytical Chemistry, Iuliu Hatieganu University of Medicine and Pharmacy, 4 L. Pasteur Street, 400349 Cluj-Napoca, Romania
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Authors to whom correspondence should be addressed.
Coatings 2020, 10(1), 36; https://doi.org/10.3390/coatings10010036
Received: 30 November 2019 / Revised: 23 December 2019 / Accepted: 27 December 2019 / Published: 1 January 2020
(This article belongs to the Special Issue Biomedical Applications of Functional Nanoparticles)
Oxidative stress may induce a series of pathophysiological modifications that are directly involved in the development of ophthalmic diseases like age-related cataract, macular degeneration or diabetic retinopathy, considered to be responsible for the majority of vision loss cases. Although various treatment options for eye diseases are available, multiple factors could limit their efficacy. Recently, the accelerated development of ophthalmic nanosystems has provided new possibilities for overcoming the limitations of existing ocular drug delivery methods. This review evaluates the current status of ophthalmic nanosystems loaded with antioxidants for the prevention and treatment of several eye diseases. View Full-Text
Keywords: nanosystems; antioxidants; ophthalmic administration nanosystems; antioxidants; ophthalmic administration
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MDPI and ACS Style

Dinte, E.; Vostinaru, O.; Samoila, O.; Sevastre, B.; Bodoki, E. Ophthalmic Nanosystems with Antioxidants for the Prevention and Treatment of Eye Diseases. Coatings 2020, 10, 36.

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