Next Article in Journal
Antimicrobial and Efflux Pump Inhibitory Activity of Carvotacetones from Sphaeranthus africanus Against Mycobacteria
Next Article in Special Issue
Antimicrobial Stewardship: From Bedside to Theory. Thirteen Examples of Old and More Recent Strategies from Everyday Clinical Practice
Previous Article in Journal
Ceftazidime-Avibactam Combination Therapy Compared to Ceftazidime-Avibactam Monotherapy for the Treatment of Severe Infections Due to Carbapenem-Resistant Pathogens: A Systematic Review and Network Meta-Analysis
Previous Article in Special Issue
Drivers of Antibiotic Resistance Transmission in Low- and Middle-Income Countries from a “One Health” Perspective—A Review
 
 
Article

Patterns of Antibiotic Prescription in Colombia: Are There Differences between Capital Cities and Municipalities?

1
Grupo de Investigación en Farmacoepidemiología y Farmacovigilancia, Universidad Tecnológica de Pereira-Audifarma S.A, 660003 Pereira, Colombia
2
Grupo de Investigación Biomedicina, Facultad de Medicina, Fundación Universitaria Autónoma de las Américas, 660003 Pereira, Colombia
3
Departament de Farmacologia, Terapèutica i Toxicología, Universitat Autònoma de Barcelona, 08193 Barcelona, Spain
*
Author to whom correspondence should be addressed.
Antibiotics 2020, 9(7), 389; https://doi.org/10.3390/antibiotics9070389
Received: 23 May 2020 / Revised: 5 July 2020 / Accepted: 6 July 2020 / Published: 8 July 2020
The use of antibiotics is the most important modifiable risk factor for the development of microorganism resistance. A cross-sectional study of outpatients receiving antibiotic prescriptions registered in a population database in Colombia was conducted. The characteristics of the consumption in capital cities and small municipalities was studied and the AWaRe classification was used. AWaRe classifies antibiotics into three stewardship groups: Access, Watch and Reserve, to emphasize the importance of their optimal use and potential harms of antimicrobial resistance. A total of 182,397 patients were prescribed an antibiotic; the most common were penicillins (38.6%), cephalosporins (30.2%) and fluoroquinolones (10.9%). ‘Access’ antibiotics (86.4%) were the most frequently prescribed, followed by ‘Watch’ antibiotics (17.0%). Being 18 or older, being male, living in a municipality, having one or more comorbidities and urinary, respiratory or gastrointestinal disorders increased the probability of receiving ‘Watch’ or ‘Reserve’ antibiotics. Penicillin and urinary antiseptic prescriptions predominated in cities, while cephalosporin and fluoroquinolone prescriptions predominated in municipalities. This analysis showed that the goal set by the WHO Access of mainly using Access antibiotics is being met, although the high use of Watch antibiotics in municipalities should be carefully studied to determine if it is necessary to design specific campaigns to improve antibiotics use. View Full-Text
Keywords: antibiotic prescription; AWaRe classification; Colombia; rural/urban consumption; fluoroquinolones; cephalosporins; drug utilization study antibiotic prescription; AWaRe classification; Colombia; rural/urban consumption; fluoroquinolones; cephalosporins; drug utilization study
MDPI and ACS Style

Machado-Alba, J.E.; Valladales-Restrepo, L.F.; Gaviria-Mendoza, A.; Machado-Duque, M.E.; Figueras, A. Patterns of Antibiotic Prescription in Colombia: Are There Differences between Capital Cities and Municipalities? Antibiotics 2020, 9, 389. https://doi.org/10.3390/antibiotics9070389

AMA Style

Machado-Alba JE, Valladales-Restrepo LF, Gaviria-Mendoza A, Machado-Duque ME, Figueras A. Patterns of Antibiotic Prescription in Colombia: Are There Differences between Capital Cities and Municipalities? Antibiotics. 2020; 9(7):389. https://doi.org/10.3390/antibiotics9070389

Chicago/Turabian Style

Machado-Alba, Jorge Enrique, Luis Fernando Valladales-Restrepo, Andrés Gaviria-Mendoza, Manuel Enrique Machado-Duque, and Albert Figueras. 2020. "Patterns of Antibiotic Prescription in Colombia: Are There Differences between Capital Cities and Municipalities?" Antibiotics 9, no. 7: 389. https://doi.org/10.3390/antibiotics9070389

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop