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Review

Diabetic Foot Ulcers: Current Advances in Antimicrobial Therapies and Emerging Treatments

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Molecular Medicine Laboratory, Unidad Academica de Medicina Humana y Ciencias de la Salud, Universidad Autonoma de Zacatecas, Carretera Zacatecas-Guadalajara Km.6. Ejido la Escondida, C.P. 98160 Zacatecas, Mexico
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Unidad Academica de Ingenieria Electrica, Universidad Autonoma de Zacatecas, Jardín Juárez 147, Centro, 98000 Zacatecas, Mexico
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Laboratorio de Sintesis Asimetrica y Bioenergetica (LSAyB), PA de Ingeniería Química, UACQ, Universidad Autonoma de Zacatecas, Carretera Zacatecas-Guadalajara Km.6. Ejido la Escondida, C.P. 98160 Zacatecas, Mexico
*
Authors to whom correspondence should be addressed.
Equal contributors.
Antibiotics 2019, 8(4), 193; https://doi.org/10.3390/antibiotics8040193
Received: 22 August 2019 / Revised: 16 October 2019 / Accepted: 17 October 2019 / Published: 24 October 2019
Diabetic foot ulcers (DFUs) are very important diabetes-related lesions that can lead to serious physical consequences like amputations of limbs and equally severe social, psychological, and economic outcomes. It is reported that up to 25% of patients with diabetes develop a DFU in their lifetime, and more than half of them become infected. Therefore, it is essential to manage infection and ulcer recovery to prevent negatives outcomes. The available information plays a significant role in keeping both physicians and patients aware of the emerging therapies against DFUs. The purpose of this review is to compile the currently available approaches in the managing and treatment of DFUs, including molecular and regenerative medicine, antimicrobial and energy-based therapies, and the use of plant extracts, antimicrobial peptides, growth factors, ozone, devices, and nano-medicine, to offer an overview of the assessment of this condition. View Full-Text
Keywords: diabetic foot ulcer; antimicrobial therapy; regenerative medicine diabetic foot ulcer; antimicrobial therapy; regenerative medicine
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MDPI and ACS Style

Ramirez-Acuña, J.M.; Cardenas-Cadena, S.A.; Marquez-Salas, P.A.; Garza-Veloz, I.; Perez-Favila, A.; Cid-Baez, M.A.; Flores-Morales, V.; Martinez-Fierro, M.L. Diabetic Foot Ulcers: Current Advances in Antimicrobial Therapies and Emerging Treatments. Antibiotics 2019, 8, 193. https://doi.org/10.3390/antibiotics8040193

AMA Style

Ramirez-Acuña JM, Cardenas-Cadena SA, Marquez-Salas PA, Garza-Veloz I, Perez-Favila A, Cid-Baez MA, Flores-Morales V, Martinez-Fierro ML. Diabetic Foot Ulcers: Current Advances in Antimicrobial Therapies and Emerging Treatments. Antibiotics. 2019; 8(4):193. https://doi.org/10.3390/antibiotics8040193

Chicago/Turabian Style

Ramirez-Acuña, Jesus Manuel, Sergio A Cardenas-Cadena, Pedro A Marquez-Salas, Idalia Garza-Veloz, Aurelio Perez-Favila, Miguel A Cid-Baez, Virginia Flores-Morales, and Margarita L Martinez-Fierro. 2019. "Diabetic Foot Ulcers: Current Advances in Antimicrobial Therapies and Emerging Treatments" Antibiotics 8, no. 4: 193. https://doi.org/10.3390/antibiotics8040193

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