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Review

Recent Developments in Methicillin-Resistant Staphylococcus aureus (MRSA) Treatment: A Review

1
Biomaterials in Medicinal Chemistry Laboratory, Department of Natural Products Chemistry, School of Chemistry, Madurai Kamaraj University, Madurai 625021, India
2
Department of Pharmacy and Pharmacology, School of Therapeutic Sciences, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg 2193, South Africa
3
Department of Biology, College of Science, Al-Zulfi, Majmaah University, Majmaah 11952, Saudi Arabia
4
Department of Pharmaceutics, College of Pharmacy, University of Hafr Al Batin, Hafar Al Batin 39524, Saudi Arabia
*
Author to whom correspondence should be addressed.
Academic Editors: Thaís Guimarães and Silvia Figueiredo Costa
Antibiotics 2022, 11(5), 606; https://doi.org/10.3390/antibiotics11050606
Received: 7 February 2022 / Revised: 28 February 2022 / Accepted: 23 March 2022 / Published: 29 April 2022
(This article belongs to the Special Issue Antimicrobial Resistance and Healthcare Associated Infections)
Staphylococcus aureus (S. aureus) is a Gram-positive bacterium that may cause life-threatening diseases and some minor infections in living organisms. However, it shows notorious effects when it becomes resistant to antibiotics. Strain variants of bacteria, viruses, fungi, and parasites that have become resistant to existing multiple antimicrobials are termed as superbugs. Methicillin is a semisynthetic antibiotic drug that was used to inhibit staphylococci pathogens. The S. aureus resistant to methicillin is known as methicillin-resistant Staphylococcus aureus (MRSA), which became a superbug due to its defiant activity against the antibiotics and medications most commonly used to treat major and minor infections. Successful MRSA infection management involves rapid identification of the infected site, culture and susceptibility tests, evidence-based treatment, and appropriate preventive protocols. This review describes the clinical management of MRSA pathogenesis, recent developments in rapid diagnosis, and antimicrobial treatment choices for MRSA. View Full-Text
Keywords: methicillin-resistant Staphylococcus aureus (MRSA); superbug; pathogenesis; antibiotics; treatment methicillin-resistant Staphylococcus aureus (MRSA); superbug; pathogenesis; antibiotics; treatment
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MDPI and ACS Style

Nandhini, P.; Kumar, P.; Mickymaray, S.; Alothaim, A.S.; Somasundaram, J.; Rajan, M. Recent Developments in Methicillin-Resistant Staphylococcus aureus (MRSA) Treatment: A Review. Antibiotics 2022, 11, 606. https://doi.org/10.3390/antibiotics11050606

AMA Style

Nandhini P, Kumar P, Mickymaray S, Alothaim AS, Somasundaram J, Rajan M. Recent Developments in Methicillin-Resistant Staphylococcus aureus (MRSA) Treatment: A Review. Antibiotics. 2022; 11(5):606. https://doi.org/10.3390/antibiotics11050606

Chicago/Turabian Style

Nandhini, Palanichamy, Pradeep Kumar, Suresh Mickymaray, Abdulaziz S. Alothaim, Jayaprakash Somasundaram, and Mariappan Rajan. 2022. "Recent Developments in Methicillin-Resistant Staphylococcus aureus (MRSA) Treatment: A Review" Antibiotics 11, no. 5: 606. https://doi.org/10.3390/antibiotics11050606

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