Next Article in Journal
Use of Novel Antibiograms to Determine the Need for Earlier Susceptibility Testing and Administration for New β-Lactam/β-Lactamase Inhibitors in the United States
Previous Article in Journal
Transinusal Pathway Removal of an Impacted Third Molar with an Unusual Approach: A Case Report and a Systematic Review of the Literature
Previous Article in Special Issue
Recent Developments in Methicillin-Resistant Staphylococcus aureus (MRSA) Treatment: A Review
Article

Microbial Landscape and Antibiotic Susceptibility Dynamics of Skin and Soft Tissue Infections in Kazakhstan 2018–2020

1
Department of Clinical Pharmacology and Evidence-Based Medicine, NCJSC Karaganda Medical University, Karaganda 100000, Kazakhstan
2
Scientific Research Laboratory, NCJSC Karaganda Medical University, Karaganda 100000, Kazakhstan
3
Department of Surgery, NCJSC Karaganda Medical University, Karaganda 100000, Kazakhstan
4
Salidat Kairbekova National Research Center for Health Development, Nur-Sultan 010000, Kazakhstan
5
National Center for Rational Use of Medicines, Nur-Sultan 010000, Kazakhstan
*
Authors to whom correspondence should be addressed.
Academic Editor: Masafumi Seki
Antibiotics 2022, 11(5), 659; https://doi.org/10.3390/antibiotics11050659
Received: 4 April 2022 / Revised: 4 May 2022 / Accepted: 11 May 2022 / Published: 13 May 2022
(This article belongs to the Special Issue Antimicrobial Resistance and Healthcare Associated Infections)
Skin and soft tissue inflammatory diseases of bacterial origin occupy a significant part of hospitalizations to emergency departments. One of the most common causes of sepsis is soft tissue infection, which accounts for about a quarter of all nosocomial infections. The aim of this study was to determine the differences in microbial landscape and antibiotic susceptibility of soft tissue infection pathogens among adults and children during the period 2018–2020. We studied 110 samples of pus admitted to the Scientific Research laboratory of the Karaganda Medical University from 2018 to 2020. Each sample was studied using the standard and express methods. The antibiotic susceptibility was determined by using the diffuse disk method in accordance with the CLSI 2018 recommendations. As such, 50% of S. epidermidis strains in children and 30% in adults were methicillin resistant. Differences in the resistance of S. aureus strains in children and adults were insignificant. Thus, methicillin-resistant S. aureus (MRSA) was not detected in children, but in adults, on the other hand, their percentage was 12.5%. The third cause of infection in adults was E. coli (13.72%), among which 75% were multidrug resistant. A. baumanii was found in 4.9% of adult patients’ samples, of which 60% were multidrug resistant. The effectiveness of the most prescribed antibiotics decreased due to the isolated strain resistance. View Full-Text
Keywords: antibiotic resistance; antibiotic susceptibility; antibiotics; soft tissue infection; skin and soft tissue infection antibiotic resistance; antibiotic susceptibility; antibiotics; soft tissue infection; skin and soft tissue infection
Show Figures

Figure 1

MDPI and ACS Style

Kaliyeva, S.S.; Lavrinenko, A.V.; Tishkambayev, Y.; Zhussupova, G.; Issabekova, A.; Begesheva, D.; Simokhina, N. Microbial Landscape and Antibiotic Susceptibility Dynamics of Skin and Soft Tissue Infections in Kazakhstan 2018–2020. Antibiotics 2022, 11, 659. https://doi.org/10.3390/antibiotics11050659

AMA Style

Kaliyeva SS, Lavrinenko AV, Tishkambayev Y, Zhussupova G, Issabekova A, Begesheva D, Simokhina N. Microbial Landscape and Antibiotic Susceptibility Dynamics of Skin and Soft Tissue Infections in Kazakhstan 2018–2020. Antibiotics. 2022; 11(5):659. https://doi.org/10.3390/antibiotics11050659

Chicago/Turabian Style

Kaliyeva, Sholpan S., Alyona V. Lavrinenko, Yerbol Tishkambayev, Gulzira Zhussupova, Aissulu Issabekova, Dinara Begesheva, and Natalya Simokhina. 2022. "Microbial Landscape and Antibiotic Susceptibility Dynamics of Skin and Soft Tissue Infections in Kazakhstan 2018–2020" Antibiotics 11, no. 5: 659. https://doi.org/10.3390/antibiotics11050659

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop