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Article

Combined Inhibitory Effect of Fir (Abies alba Mill.) Honeydew Honey and Probiotic Bacteria Lactiplantibacillus plantarum on the Growth of Salmonella enterica Serotype Typhimurium

1
Department of Microbiology and Parasitology, Faculty of Medicine, University of Rijeka, Brace Branchetta 20, 51000 Rijeka, Croatia
2
Analytical Toxicology and Mineral Metabolism Unit, Institute for Medical Research and Occupational Health, 10000 Zagreb, Croatia
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Faculty of Health Studies, University of Rijeka, Viktora Cara Emina 5, 51000 Rijeka, Croatia
4
Department of Environmental Health, Teaching Institute of Public Health of Primorsko-Goranska County, 51000 Rijeka, Croatia
5
Bioinstitut d.o.o., R. Steinera 7, 40000 Čakovec, Croatia
*
Author to whom correspondence should be addressed.
Academic Editor: Piotr Szweda
Antibiotics 2022, 11(2), 145; https://doi.org/10.3390/antibiotics11020145
Received: 22 December 2021 / Revised: 17 January 2022 / Accepted: 22 January 2022 / Published: 24 January 2022
Honey is a natural food consisting mainly of sugars, enzymes, amino acids, organic acids, vitamins, minerals and aromatic substances. In addition to specific organoleptic properties, honey also has other components that contribute to its nutritional and health value. Proteins, vitamins, minerals, organic acids and phenolic compounds, the most variable components of honey, are predominantly responsible for its strong bioactive effect. Honeydew honey is a less known type of honey with outstanding antimicrobial and antioxidant properties that also demonstrates prebiotic effects and can promote the growth of probiotic bacteria. Foodborne illnesses can be prevented by using probiotic strains in combination with prebiotics. The aim of this study was for the first time to determine potential synergistic antimicrobial effect of fir (Abies alba Mill.) honeydew honey (HS) and probiotic bacteria Lactiplantibacillus plantarum on Salmonella enterica serotype Typhimurium, a primary cause of foodborne illnesses. The effect of three different samples of fir honeydew honey on the growth of L. plantarum in de Man, Rogosa and Sharpe (MRS) medium and the potential synergistic effect of HSs and L. plantarum on the growth of S. Typhimurium in the Brain Heart Infusion (BHI) medium were examined. The results indicate that concentrations of 1 and 5% of all three HS samples stimulate the growth and metabolic activity of L. plantarum, while a concentration of 10% inhibits the growth of L. plantarum. The concentration of 5% of all three HS and L. plantarum combined inhibits the growth of S. Typhimurium in BHI broth. Fir honeydew honey showed potential prebiotic properties and antimicrobial activity, both of which can synergistically enhance the probiotic efficacy of L. plantarum against S. Typhimurium To conclude, the combination of fir honeydew honey and L. plantarum represents a successful combination against S. Typhimurium and additional experiments are necessary regarding the mechanisms of their combined effect. View Full-Text
Keywords: symbiotic; Lactiplantibacillus; honeydew honey; Salmonella symbiotic; Lactiplantibacillus; honeydew honey; Salmonella
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MDPI and ACS Style

Mežnarić, S.; Brčić Karačonji, I.; Crnković, G.; Lesar, A.; Pavlešić, T.; Vučković, D.; Gobin, I. Combined Inhibitory Effect of Fir (Abies alba Mill.) Honeydew Honey and Probiotic Bacteria Lactiplantibacillus plantarum on the Growth of Salmonella enterica Serotype Typhimurium. Antibiotics 2022, 11, 145. https://doi.org/10.3390/antibiotics11020145

AMA Style

Mežnarić S, Brčić Karačonji I, Crnković G, Lesar A, Pavlešić T, Vučković D, Gobin I. Combined Inhibitory Effect of Fir (Abies alba Mill.) Honeydew Honey and Probiotic Bacteria Lactiplantibacillus plantarum on the Growth of Salmonella enterica Serotype Typhimurium. Antibiotics. 2022; 11(2):145. https://doi.org/10.3390/antibiotics11020145

Chicago/Turabian Style

Mežnarić, Silvestar, Irena Brčić Karačonji, Goranka Crnković, Andrija Lesar, Tomislav Pavlešić, Darinka Vučković, and Ivana Gobin. 2022. "Combined Inhibitory Effect of Fir (Abies alba Mill.) Honeydew Honey and Probiotic Bacteria Lactiplantibacillus plantarum on the Growth of Salmonella enterica Serotype Typhimurium" Antibiotics 11, no. 2: 145. https://doi.org/10.3390/antibiotics11020145

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