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What Electrochemical Biosensors Can Do for Forensic Science? Unique Features and Applications

Departamento de Química Analítica, Facultad de CC. Químicas, Universidad Complutense de Madrid, E-28040 Madrid, Spain
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Biosensors 2019, 9(4), 127; https://doi.org/10.3390/bios9040127
Received: 7 October 2019 / Revised: 23 October 2019 / Accepted: 25 October 2019 / Published: 29 October 2019
(This article belongs to the Special Issue The Potential of (bio)sensors for the Forensic Sciences)
This article critically discusses the latest advances in the use of voltammetric, amperometric, potentiometric, and impedimetric biosensors for forensic analysis. Highlighted examples that show the advantages of these tools to develop methods capable of detecting very small concentrations of analytes and provide selective determinations through analytical responses, without significant interferences from other components of the samples, are presented and discussed, thus stressing the great versatility and utility of electrochemical biosensors in this growing research field. To illustrate this, the determination of substances with forensic relevance by using electrochemical biosensors reported in the last five years (2015–2019) are reviewed. The different configurations of enzyme or affinity biosensors used to solve analytical problems related to forensic practice, with special attention to applications in complex samples, are considered. Main prospects, challenges to focus, such as the fabrication of devices for rapid analysis of target analytes directly on-site at the crime scene, or their widespread use and successful applications to complex samples of interest in forensic analysis, and future efforts, are also briefly discussed. View Full-Text
Keywords: electrochemical biosensors; forensic analysis; poisons; drugs; toxins; explosives; chemical and biological weapons electrochemical biosensors; forensic analysis; poisons; drugs; toxins; explosives; chemical and biological weapons
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Yáñez-Sedeño, P.; Agüí, L.; Campuzano, S.; Pingarrón, J.M. What Electrochemical Biosensors Can Do for Forensic Science? Unique Features and Applications. Biosensors 2019, 9, 127.

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