Next Article in Journal
Response Surface Methodology for the Optimisation of Electrochemical Biosensors for Heavy Metals Detection
Next Article in Special Issue
Surface Enhanced Raman Spectroscopy of Lactoferrin Adsorbed on Silvered Porous Silicon Covered with Graphene
Previous Article in Journal
Rapid Drop-Test for Lectin Binding with Glycopolymer-Coated Optical Ring Resonators
Previous Article in Special Issue
Detection of Metabolic Changes Induced via Drug Treatments in Live Cancer Cells and Tissue Using Raman Imaging Microscopy
Article Menu

Export Article

Open AccessArticle
Biosensors 2019, 9(1), 25; https://doi.org/10.3390/bios9010025

The Recent Advances in Raman Microscopy and Imaging Techniques for Biosensors

Thermo Fisher Scientific, 2 Radcliff Rd., Tewksbury, MA 01876, USA
Received: 7 January 2019 / Revised: 30 January 2019 / Accepted: 6 February 2019 / Published: 12 February 2019
(This article belongs to the Special Issue Applications of Raman Techniques in Biosensing)
Full-Text   |   PDF [4116 KB, uploaded 27 February 2019]   |  

Abstract

Raman microspectroscopy is now well established as one of the most powerful analytical techniques for a diverse range of applications in physical (material) and biological sciences. Consequently, the technique provides exceptional analytical opportunities to the science and technology of biosensing due to its capability to analyze both parts of a biosensor system—biologically sensitive components, and a variety of materials and systems used in physicochemical transducers. Recent technological developments in Raman spectral imaging have brought additional possibilities in two- and three-dimensional (2D and 3D) characterization of the biosensor’s constituents and their changes on a submicrometer scale in a label-free, real-time nondestructive method of detection. In this report, the essential components and features of a modern confocal Raman microscope are reviewed using the instance of Thermo Scientific DXRxi Raman imaging microscope, and examples of the potential applications of Raman microscopy and imaging for constituents of biosensors are presented. View Full-Text
Keywords: Raman; spectroscopy; microscopy; imaging; biological cells; SWCNT Raman; spectroscopy; microscopy; imaging; biological cells; SWCNT
Figures

Graphical abstract

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
SciFeed

Share & Cite This Article

MDPI and ACS Style

Rzhevskii, A. The Recent Advances in Raman Microscopy and Imaging Techniques for Biosensors. Biosensors 2019, 9, 25.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Biosensors EISSN 2079-6374 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top