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Aptasensors Based on Whispering Gallery Mode Resonators

Istituto di Fisica Applicata Nello Carrara (IFAC CNR), Via Madonna del Piano 10, 50019 Sesto Fiorentino, Firenze, Italy
Author to whom correspondence should be addressed.
Academic Editor: Giovanna Marrazza
Biosensors 2016, 6(3), 28;
Received: 29 April 2016 / Revised: 7 June 2016 / Accepted: 13 June 2016 / Published: 16 July 2016
(This article belongs to the Special Issue Aptamer Sensors)
In this paper, we review the literature on optical evanescent field sensing in resonant cavities where aptamers are used as biochemical receptors. The combined advantages of highly sensitive whispering gallery mode resonator (WGMR)-based transducers, and of the unique properties of aptamers make this approach extremely interesting in the medical field, where there is a particularly high need for devices able to provide real time diagnosis for cancer, infectious diseases, or strokes. However, despite the superior performances of aptamers compared to antibodies and WGMR to other evanescent sensors, there is not much literature combining both types of receptors and transducers. Up to now, the WGMR that have been used are silica microspheres and silicon oxynitride (SiON) ring resonators. View Full-Text
Keywords: aptamers; whispering gallery mode resonators; microspheres; integrated rings; optical sensors aptamers; whispering gallery mode resonators; microspheres; integrated rings; optical sensors
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MDPI and ACS Style

Nunzi Conti, G.; Berneschi, S.; Soria, S. Aptasensors Based on Whispering Gallery Mode Resonators. Biosensors 2016, 6, 28.

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