Next Article in Journal
Performance-Enhanced 365 nm UV LEDs with Electrochemically Etched Nanoporous AlGaN Distributed Bragg Reflectors
Next Article in Special Issue
Electrochemical DNA Biosensors Based on Labeling with Nanoparticles
Previous Article in Journal
A Photocleavable Amphiphilic Prodrug Self-Assembled Nanoparticles with Effective Anticancer Activity In Vitro
Previous Article in Special Issue
Nanomaterials-Based Colorimetric Immunoassays
Open AccessReview

Gold Nanoparticle-Based Colorimetric Strategies for Chemical and Biological Sensing Applications

1
Biomedical Technology and Device Research Laboratories, Industrial Technology Research Institute, Hsinchu 310, Taiwan
2
Department of Obstetrics and Gynecology, Mackay Memorial Hospital, Taipei 104, Taiwan
3
Graduate Institute of Biomedical Electronics and Bioinformatics, National Taiwan University, Taipei 106, Taiwan
4
Department of Biomedical Engineering, National Taiwan University, Taipei 106, Taiwan
*
Authors to whom correspondence should be addressed.
Nanomaterials 2019, 9(6), 861; https://doi.org/10.3390/nano9060861
Received: 13 May 2019 / Revised: 31 May 2019 / Accepted: 3 June 2019 / Published: 6 June 2019
(This article belongs to the Special Issue Nanomaterials for Immunosensors and DNA Sensors)
Gold nanoparticles are popularly used in biological and chemical sensors and their applications owing to their fascinating chemical, optical, and catalytic properties. Particularly, the use of gold nanoparticles is widespread in colorimetric assays because of their simple, cost-effective fabrication, and ease of use. More importantly, the gold nanoparticle sensor response is a visual change in color, which allows easy interpretation of results. Therefore, many studies of gold nanoparticle-based colorimetric methods have been reported, and some review articles published over the past years. Most reviews focus exclusively on a single gold nanoparticle-based colorimetric technique for one analyte of interest. In this review, we focus on the current developments in different colorimetric assay designs for the sensing of various chemical and biological samples. We summarize and classify the sensing strategies and mechanism analyses of gold nanoparticle-based detection. Additionally, typical examples of recently developed gold nanoparticle-based colorimetric methods and their applications in the detection of various analytes are presented and discussed comprehensively. View Full-Text
Keywords: gold nanoparticle; colorimetric assay; aggregation of AuNPs; etching of AuNPs; growth of AuNPs; nanoenzyme gold nanoparticle; colorimetric assay; aggregation of AuNPs; etching of AuNPs; growth of AuNPs; nanoenzyme
Show Figures

Figure 1

MDPI and ACS Style

Chang, C.-C.; Chen, C.-P.; Wu, T.-H.; Yang, C.-H.; Lin, C.-W.; Chen, C.-Y. Gold Nanoparticle-Based Colorimetric Strategies for Chemical and Biological Sensing Applications. Nanomaterials 2019, 9, 861.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop