Next Article in Journal
The Impact of the Electric Field on Surface Condensation of Water Vapor: Insight from Molecular Dynamics Simulation
Next Article in Special Issue
Impaired Liver Size and Compromised Neurobehavioral Activity are Elicited by Chitosan Nanoparticles in the Zebrafish Embryo Model
Previous Article in Journal
Magnetofluorescent Nanocomposite Comprised of Carboxymethyl Dextran Coated Superparamagnetic Iron Oxide Nanoparticles and β-Diketon Coordinated Europium Complexes
Previous Article in Special Issue
pH-Sensitive Poly(β-amino ester)s Nanocarriers Facilitate the Inhibition of Drug Resistance in Breast Cancer Cells
Article Menu
Issue 1 (January) cover image

Export Article

Open AccessArticle

Composite Nanofibers Containing Multiwall Carbon Nanotubes as Biodegradable Membranes in Reconstructive Medicine

1
Institute of Non-Ferrous Metals, 44-100 Gliwice, Poland
2
Katedra Chirurgii Czaszkowo-Szczękowo-Twarzowej i Chirurgii Stomatologicznej, Śląski Uniwersytet Medyczny w Katowicach, 40-027 Katowice, Poland
3
Department of Anatomy, School of Health Sciences in Katowice, Medical University of Silesia, 40-055 Katowice, Poland
4
Biosystems Group, Institute of Automatic Control, Faculty of Automatics, Electronics and Informatics, and Biotechnology Centre, Silesian University of Technology, 44-100 Gliwice, Poland
5
ENT Department, School of Medicine in Katowice, Medical University of Silesia in Katowice, 40-055 Katowice, Poland
6
Institute of Metallurgy and Material Science Polish Academy of Sciences, 30-059 Kraków, Poland
7
Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej Śląski, Zakład Biologii Molekularnej Katedry Biologii Molekularnej, Uniwersytet Medyczny w Katowicach, 40-055 Katowice, Poland
8
Centre of Biotechnology, Silesian University of Technology, 44-100 Gliwice, Poland
9
Centre de Biophysique Moléculaire, UPR4301 CNRS CS80054, Rue Charles Sadron, 45071 Orleans CEDEX 2, France
*
Authors to whom correspondence should be addressed.
Nanomaterials 2019, 9(1), 63; https://doi.org/10.3390/nano9010063
Received: 16 November 2018 / Revised: 23 December 2018 / Accepted: 27 December 2018 / Published: 4 January 2019
(This article belongs to the Special Issue Biomedical Applications of Nanotechnology)
  |  
PDF [5352 KB, uploaded 4 January 2019]
  |  

Abstract

We have tested titanium (Ti) plates that are used for bone reconstruction in maxillofacial surgery, in combination with five types of novel long-resorbable biomaterials: (i) PCL0—polycaprolactone without additives, (ii) PCLMWCNT—polycaprolactone with the addition of multiwall carbon nanotubes (MWCNT), (iii) PCLOH—polycaprolactone doped with multiwall carbon nanotubes (MWCNT) containing –OH hydroxyl groups, (iv) PCLCOOH—polycaprolactone with the addition of multiwall carbon nanotubes (MWCNT) containing carboxyl groups, and (v) PCLTI—polycaprolactone with the addition of Ti nanoparticles. The structure and properties of the obtained materials have been examined with the use of Scanning Electron Microscopy (SEM), Transmission Electron Microscopy (TEM), Raman spectroscopy, Fourier transform infrared spectroscopy (FTIR), and/or X-ray powder diffraction (XRD). Titanium BR plates have been covered with: (i) PCL0 fibers (PCL0BR—connection plates), (ii) PCLMWCNT fibers (PCLMWCNTBR—plates), (iii) PCLOH fibers (PCLOHBR—plates), (iv) PCLCOOH (PCLCOOHBR—plates), (v) PCLTI fiber (PCLTIBR—connection plates). Such modified titanium plates were exposed to X-ray doses corresponding to those applied in head and neck tumor treatment. The potential leaching of toxic materials upon the irradiation of such modified titanium plates, and their effect on normal human dermal fibroblasts (NHDF) have been assessed by MTT assay. The presented results show variable biological responses depending on the modifications to titanium plates. View Full-Text
Keywords: electrospinning; multiwall carbon nanotubes; polycaprolactone; reconstructive medicine; titanium electrospinning; multiwall carbon nanotubes; polycaprolactone; reconstructive medicine; titanium
Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
SciFeed

Share & Cite This Article

MDPI and ACS Style

Hudecki, A.; Łyko-Morawska, D.; Likus, W.; Skonieczna, M.; Markowski, J.; Wilk, R.; Kolano-Burian, A.; Maziarz, W.; Adamska, J.; Łos, M.J. Composite Nanofibers Containing Multiwall Carbon Nanotubes as Biodegradable Membranes in Reconstructive Medicine. Nanomaterials 2019, 9, 63.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Nanomaterials EISSN 2079-4991 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top