Next Article in Journal
Static and Dynamic Biomaterial Engineering for Cell Modulation
Next Article in Special Issue
Nanomaterials in Drug Delivery Applications
Previous Article in Journal
Aptamer-Adjusted Carbon Dot Catalysis-Silver Nanosol SERS Spectrometry for Bisphenol A Detection
Previous Article in Special Issue
Accumulation and Effect of Silver Nanoparticles Functionalized with Spirulina platensis on Rats
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
Nanomaterials
Volume 12
Issue 8
10.3390/nano12081376
nanomaterials-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles
first_page
settings
Order Article Reprints
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Review

Nanocarriers for Drug Delivery: An Overview with Emphasis on Vitamin D and K Transportation

by
Andreea Crintea
1,
Alina Gabriela Dutu
1,
Alina Sovrea
2,
Anne-Marie Constantin
2,
Gabriel Samasca
3,
Aurelian Lucian Masalar
1,
Brigitta Ifju
1,
Eugen Linga
1,
Lidia Neamti
1,
Rares Andrei Tranca
4,
Zsolt Fekete
5,
Ciprian Nicolae Silaghi
1,* and
Alexandra Marioara Craciun
1
1
Department of Medical Biochemistry, Iuliu Hațieganu University of Medicine and Pharmacy, 400349 Cluj-Napoca, Romania
2
Department of Morphological Sciences, Iuliu Hațieganu University of Medicine and Pharmacy, 400349 Cluj-Napoca, Romania
3
Department of Immunology, Iuliu Hatieganu University of Medicine and Pharmacy, 400349 Cluj-Napoca, Romania
4
Department of Molecular Biology and Biotechnology, Babeș-Bolyai University, 400084 Cluj-Napoca, Romania
5
Department of Oncology, Iuliu Hațieganu University of Medicine and Pharmacy, 400349 Cluj-Napoca, Romania
*
Author to whom correspondence should be addressed.
Nanomaterials 2022, 12(8), 1376; https://doi.org/10.3390/nano12081376
Submission received: 16 February 2022 / Revised: 6 April 2022 / Accepted: 12 April 2022 / Published: 17 April 2022
(This article belongs to the Special Issue Nanoparticles Drug Delivery)
Browse Figures
Versions Notes

Abstract

Mounting evidence shows that supplementation with vitamin D and K or their analogs induces beneficial effects in various diseases, e.g., osteoarticular, cardiovascular, or carcinogenesis. The use of drugs delivery systems via organic and inorganic nanocarriers increases the bioavailability of vitamins and analogs, enhancing their cellular delivery and effects. The nanotechnology-based dietary supplements and drugs produced by the food and pharmaceutical industries overcome the issues associated with vitamin administration, such as stability, absorption or low bioavailability. Consequently, there is a continuous interest in optimizing the carriers’ systems in order to make them more efficient and specific for the targeted tissue. In this pioneer review, we try to circumscribe the most relevant aspects related to nanocarriers for drug delivery, compare different types of nanoparticles for vitamin D and K transportation, and critically address their benefits and disadvantages.
Keywords: nanocarriers; drug delivery; vitamin D; vitamin K nanocarriers; drug delivery; vitamin D; vitamin K

Share and Cite

MDPI and ACS Style

Crintea, A.; Dutu, A.G.; Sovrea, A.; Constantin, A.-M.; Samasca, G.; Masalar, A.L.; Ifju, B.; Linga, E.; Neamti, L.; Tranca, R.A.; et al. Nanocarriers for Drug Delivery: An Overview with Emphasis on Vitamin D and K Transportation. Nanomaterials 2022, 12, 1376. https://doi.org/10.3390/nano12081376

AMA Style

Crintea A, Dutu AG, Sovrea A, Constantin A-M, Samasca G, Masalar AL, Ifju B, Linga E, Neamti L, Tranca RA, et al. Nanocarriers for Drug Delivery: An Overview with Emphasis on Vitamin D and K Transportation. Nanomaterials. 2022; 12(8):1376. https://doi.org/10.3390/nano12081376

Chicago/Turabian Style

Crintea, Andreea, Alina Gabriela Dutu, Alina Sovrea, Anne-Marie Constantin, Gabriel Samasca, Aurelian Lucian Masalar, Brigitta Ifju, Eugen Linga, Lidia Neamti, Rares Andrei Tranca, and et al. 2022. "Nanocarriers for Drug Delivery: An Overview with Emphasis on Vitamin D and K Transportation" Nanomaterials 12, no. 8: 1376. https://doi.org/10.3390/nano12081376

APA Style

Crintea, A., Dutu, A. G., Sovrea, A., Constantin, A.-M., Samasca, G., Masalar, A. L., Ifju, B., Linga, E., Neamti, L., Tranca, R. A., Fekete, Z., Silaghi, C. N., & Craciun, A. M. (2022). Nanocarriers for Drug Delivery: An Overview with Emphasis on Vitamin D and K Transportation. Nanomaterials, 12(8), 1376. https://doi.org/10.3390/nano12081376

Note that from the first issue of 2016, this journal uses article numbers instead of page numbers. See further details here.

Article Metrics

Back to TopTop