The Antibacterial Properties of Nanocomposites Based on Carbon Nanotubes and Metal Oxides Functionalized with Azithromycin and Ciprofloxacin
Abstract
:1. Introduction
2. Materials and Methods
3. Synthesis of Nanocomposites
3.1. MWCNT-COOH/Fe3O4 Synthesis
3.2. MWCNT-COOH/Fe3O4/NiO or CuO Synthesis
3.3. Synthesis of Nanocomposites MWCNT-COOH/Antibiotic, MWCNT-COOH/Fe3O4/Antibiotic, and MWCNT-COOH/Fe3O4/MO/Antibiotic
4. Results and Discussion
4.1. Morphological Characterization
4.2. FTIR Analysis
4.3. Antibacterial Activity
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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MWCNT | MWCNT-COOH | MWCNT-COOH/Fe3O4 | MWCNT-COOH/Fe3O4/NiO | MWCNT-COOH/Fe3O4/CuO | Azi | Cip | |
---|---|---|---|---|---|---|---|
E. coli | 0 ± 0 | 0 ± 0 | 0 ± 0 | 8 ± 11.3 * | 7.5 ± 10.6 * | 21 ± 2.8 | 31.2 ± 0.3 |
P. aeruginosa | 0 ± 0 | 0 ± 0 | 0 ± 0 | 0 ± 0 | 0 ± 0 | 25 | 30.5 ± 0.7 |
S. aureus | 0 ± 0 | 0 ± 0 | 0 ± 0 | 8.5 ± 2.1 | 14.75 ± 2.4 | 21.5 ± 1.4 | 22 |
E. faecalis | 0 ± 0 | 0 ± 0 | 0 ± 0 | 0 | 0 ± 0 | 21.5 ± 0.7 | 25 ± 0.3 |
MWCNT-COOH/Azi | MWCNT-COOH/Cip | MWCNT-COOH/Fe3O4/Azi | MWCNT-COOH/Fe3O4/Cip | MWCNT-COOH/Fe3O4/NiO/Azi | MWCNT-COOH/Fe3O4/NiO/Cip | MWCNT-COOH/Fe3O4/CuO/Azi | MWCNT-COOH/Fe3O4/CuO/Cip | |
---|---|---|---|---|---|---|---|---|
E. coli | 23 ± 2.8 | 40 ± 0 | 0 ± 0 | 44.25 ± 6.7 | 0 ± 0 | 35 ± 0 | 12.25 ± 0.35 | 39.5 ± 13.4 |
P. aeruginosa | 19 ± 0 | 40.75 ± 0.3 | 0 ± 0 | 43.5 ± 4.9 | 0 ± 0 | 38.5 ± 12 | 25.5 ± 0.7 | 32.5 ± 10.6 |
S. aureus | 16.25 ± 0.35 | 38 ± 2.8 | 8 ± 1.4 | 40.25 ± 6.7 | 8.5 ± 2.1 | 31.75 ± 4.5 | 11.75 ± 1 | 35.25 ± 0.3 |
E. faecalis | 11.25 ± 0.35 | 28.75 ± 1.7 | 0 ± 0 | 29 ± 1.4 | 8.5 ± 0.7 | 27 ± 1.4 | 7.5 ± 0.7 | 23.75 ± 3.1 |
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Stegarescu, A.; Lung, I.; Ciorîță, A.; Kacso, I.; Opriș, O.; Soran, M.-L.; Soran, A. The Antibacterial Properties of Nanocomposites Based on Carbon Nanotubes and Metal Oxides Functionalized with Azithromycin and Ciprofloxacin. Nanomaterials 2022, 12, 4115. https://doi.org/10.3390/nano12234115
Stegarescu A, Lung I, Ciorîță A, Kacso I, Opriș O, Soran M-L, Soran A. The Antibacterial Properties of Nanocomposites Based on Carbon Nanotubes and Metal Oxides Functionalized with Azithromycin and Ciprofloxacin. Nanomaterials. 2022; 12(23):4115. https://doi.org/10.3390/nano12234115
Chicago/Turabian StyleStegarescu, Adina, Ildiko Lung, Alexandra Ciorîță, Irina Kacso, Ocsana Opriș, Maria-Loredana Soran, and Albert Soran. 2022. "The Antibacterial Properties of Nanocomposites Based on Carbon Nanotubes and Metal Oxides Functionalized with Azithromycin and Ciprofloxacin" Nanomaterials 12, no. 23: 4115. https://doi.org/10.3390/nano12234115